Evidence map›Paper›PMID 34853433›Full record

ArticleBone marrow transplantation2022

Impact of donor-derived CD34 + infused cell dose on outcomes of patients undergoing allo-HCT following reduced intensity regimen for myelofibrosis: a study from the Chronic Malignancies Working Party of the EBMT.

Tomasz Czerw, Simona Iacobelli, Vittoria Malpassuti, Linda Koster, Nicolaus Kröger, Marie Robin, Johan Maertens, Patrice Chevallier, Emma Watz, Xavier Poiré and 15 more

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Bone marrow transplantation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
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  4. Review
  5. Article
  6. Review
  7. Review
  8. Myelofibrosis: let's go high!Bone marrow transplantation · 2021
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

25 authors at 20 institutions in 11 countries.

Tomasz CzerwMaria Skłodowska-Curie National Research Institute of Oncology, Gliwice Branch, Poland. tomasz.czerw@io.gliwice.pl.ORCID http://orcid.org/0000-0003-3108-4035
Simona IacobelliDepartment of Biology, Tor Vergata University, Rome, Italy.
Vittoria MalpassutiDepartment of Biology, Tor Vergata University, Rome, Italy.
Linda KosterEBMT Data Office, Leiden, Netherlands.
Nicolaus KrögerUniversity Hospital Eppendorf, Hamburg, Germany.ORCID http://orcid.org/0000-0001-5103-9966
Marie RobinHopital Saint Louis, Assistance Publique Hôpitaux de Paris, Université de Paris, Paris, France.ORCID http://orcid.org/0000-0003-1388-9876
Johan MaertensUniversity Hospital Gasthuisberg, Leuven, Belgium.
Patrice ChevallierCHU Nantes, Nantes, France.
Emma WatzKarolinska University Hospital, Stockholm, Sweden.
Xavier PoiréCliniques Universitaires St. Luc, Brussels, Belgium.ORCID http://orcid.org/0000-0003-1897-0227
John A SnowdenSheffield Teaching Hospitals NHS Trust, Sheffield, UK.
Jürgen KuballUniversity Medical Centre, Utrecht, Netherlands.ORCID http://orcid.org/0000-0002-3914-7806
Francesca KinsellaUniversity Hospital Birmingham NHS Trust, Birmingham, UK.ORCID http://orcid.org/0000-0002-6022-2567
Didier BlaiseInstitut Paoli Calmettes, Marseille, France.ORCID http://orcid.org/0000-0002-5684-9447
Péter ReményiDél-pesti Centrumkórház, Budapest, Hungary.
Jean-Baptiste MearCentre Hospitalier Universitaire de Rennes, Rennes, France.
Jörg CammengaUniversity Hospital, Linkoeping, Sweden.
Marie Thérèse RubioCHRU BRABOIS, Vandoeuvre Les Nancy, France.
Sebastien MauryHôpital Henri Mondor, Creteil, France.
Etienne DaguindauHopital Jean Minjoz, Besancon, France.
Damian FinneganBelfast City Hospital, Belfast, UK.
Patrick HaydenTrinity College Dublin, St. James's Hospital, Dublin, Ireland.ORCID http://orcid.org/0000-0003-1374-4503
Juan Carlos Hernández-BoludaHospital Clínico Universitario-INCLIVA, University of Valencia, Valencia, Spain.ORCID http://orcid.org/0000-0002-4289-3113
Donal McLornanGuys' and St. Thomas' NHS Foundation Trust and University College London Hospitals, London, UK.ORCID http://orcid.org/0000-0003-1224-091X
Ibrahim Yakoub-AghaCHfU de Lille, Université de Lille, INSERM U1286, Infinite, 59000, Lille, France.ORCID http://orcid.org/0000-0003-4524-8782
University of Rome Tor Vergata · ITCentre Hospitalier Régional et Universitaire de Nancy · FRCentre Hospitalier Universitaire de Nantes · FRCentre Hospitalier Universitaire de Rennes · FRCliniques Universitaires Saint-Luc · BEEuropean Society for Blood and Marrow Transplantation · NLGuy's and St Thomas' NHS Foundation Trust · GBHôpital Privé Jean Mermo · FRInserm · FRInstitut Paoli-Calmettes · FRJahn Ferenc Dél-Pesti Kórház és Rendelőintézet · HUKarolinska University Hospital · SELinköping University Hospital · SESheffield Teaching Hospitals NHS Foundation Trust · GBThe Maria Sklodowska-Curie National Research Institute of Oncology · PLTrinity College Dublin · IEUniversitair Ziekenhuis Leuven · BEUniversitat de València · ESUniversität Hamburg · DEUniversité Paris Cité · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The optimal CD34 + cell dose in the setting of RIC allo-HCT for myelofibrosis (MF) remains unknown. We retrospectively analyzed 657 patients with primary or secondary MF transplanted with use of peripheral blood (PB) stem cells after fludarabine/melphalan or fludarabine/busulfan RIC regimen. Median patient age was 58 (range, 22-76) years. Donors were HLA-identical sibling (MSD) or unrelated (UD). Median follow-up was 46 (2-194) months. Patients transplanted with higher doses of CD34 + cells (>7.0 × 10

Indexed as

Graft vs Host DiseaseHematopoietic Stem Cell TransplantationNeoplasmsPrimary MyelofibrosisAdultAgedHumansMiddle AgedRetrospective StudiesTransplantation ConditioningUnrelated DonorsYoung Adult

Identifiers

PMID34853433
OpenAlexW3216799945

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.