Evidence map›Paper›PMID 34853413›Full record

ArticleEuropean journal of clinical nutrition2022

Impact of religious fasting on metabolic and hematological profile in both dyslipidemic and non-dyslipidemic fasters.

Andreas S Papazoglou, Dimitrios V Moysidis, Christos Tsagkaris, Ioannis Vouloagkas, Efstratios Karagiannidis, Anastasios Kartas, Nikolaos Vlachopoulos, Georgios Konstantinou, Georgios Sofidis, Nikolaos Stalikas and 7 more

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In one paragraph

Article in European journal of clinical nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 4 institutions in 1 country.

Andreas S Papazoglou1st Cardiology Department, AHEPA University General Hospital of Thessaloniki, Thessaloniki, Greece.ORCID http://orcid.org/0000-0003-4981-8121
Dimitrios V Moysidis *1st Cardiology Department, AHEPA University General Hospital of Thessaloniki, Thessaloniki, Greece.ORCID http://orcid.org/0000-0001-9083-0267
Christos Tsagkaris *University of Crete, Faculty of Medicine, Heraklion, Greece.
Ioannis Vouloagkas1st Cardiology Department, AHEPA University General Hospital of Thessaloniki, Thessaloniki, Greece.
Efstratios Karagiannidis1st Cardiology Department, AHEPA University General Hospital of Thessaloniki, Thessaloniki, Greece.
Anastasios Kartas1st Cardiology Department, AHEPA University General Hospital of Thessaloniki, Thessaloniki, Greece.
Nikolaos Vlachopoulos251 Hellenic Air Force General Hospital, Athens, Greece.ORCID http://orcid.org/0000-0002-7876-9990
Georgios Konstantinou251 Hellenic Air Force General Hospital, Athens, Greece.
Georgios Sofidis1st Cardiology Department, AHEPA University General Hospital of Thessaloniki, Thessaloniki, Greece.
Nikolaos Stalikas1st Cardiology Department, AHEPA University General Hospital of Thessaloniki, Thessaloniki, Greece.
Eleftherios PanterisBiomic_AUTh, Center for Interdisciplinary Research and Innovation (CIRI-AUTH), Balkan Center, B1.4, 10th km Thessaloniki-Thermi Rd, 8318, GR 57001, Thessaloniki, Greece.
Olga DedaBiomic_AUTh, Center for Interdisciplinary Research and Innovation (CIRI-AUTH), Balkan Center, B1.4, 10th km Thessaloniki-Thermi Rd, 8318, GR 57001, Thessaloniki, Greece.
Nikolaos Otountzidis1st Cardiology Department, AHEPA University General Hospital of Thessaloniki, Thessaloniki, Greece.
Haralambos Karvounis1st Cardiology Department, AHEPA University General Hospital of Thessaloniki, Thessaloniki, Greece.
Helen GikaBiomic_AUTh, Center for Interdisciplinary Research and Innovation (CIRI-AUTH), Balkan Center, B1.4, 10th km Thessaloniki-Thermi Rd, 8318, GR 57001, Thessaloniki, Greece.
Georgios TheodoridisBiomic_AUTh, Center for Interdisciplinary Research and Innovation (CIRI-AUTH), Balkan Center, B1.4, 10th km Thessaloniki-Thermi Rd, 8318, GR 57001, Thessaloniki, Greece.
Georgios Sianos1st Cardiology Department, AHEPA University General Hospital of Thessaloniki, Thessaloniki, Greece. gsianos@auth.gr.ORCID http://orcid.org/0000-0002-3042-0757
AHEPA University Hospital · GRHellenic Air Force · GRAristotle University of Thessaloniki · GRUniversity of Crete · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesReligious fasting (RF) is practiced annually by millions of Christian and Muslim followers worldwide. Scarce data exist on the impact of RF on the metabolic and hematological profile of individuals with or without dyslipidemia. SUBJECTS/

methodsThe present study included: (i) 60 Greek Orthodox participants, 30 with dyslipidemia and 30 without dyslipidemia, who abstained from meat, fish and dairy products for seven consecutive weeks, and (ii) 15 young, non-dyslipidemic Muslim participants abstaining totally from food and liquid from dawn till sunset during 30 days. Biochemical (iron, ferritin, vitamin B12, calcium, low-density lipoprotein (LDL), high-density lipoprotein (HDL), total cholesterol (TC), triglyceride and fasting glucose) and hematological (hemoglobin, hematocrit) serum blood test results of study participants were measured pre- and post- RF (at weeks 0 and 7 for Orthodox participants and at weeks 0 and 4 for Muslim participants).

resultsIn dyslipidemic and non-dyslipidemic Orthodox participants, a significant reduction of fasting glucose, HDL, LDL and TC levels was found post-RF. Hemoglobin, hematocrit, iron and ferritin levels were significantly increased, while post-RF vitamin B12 and calcium levels were substantially decreased. Subanalysis between dyslipidemic and non-dyslipidemic Orthodox participants revealed a greater decrease of cholesterol levels in the former. In Muslim participants, triglyceride, LDL and total cholesterol levels were increased post-RF (all p values < 0.05).

conclusionsOur study adds to the existing literature evidence about the significant impact of RF on metabolic and hematological profiles of Orthodox and Muslim followers. The prevention of calcium and B12 deficiency during Orthodox RF by supplement consumption as well as the protection from dehydration and dysregulation of lipid metabolism during Ramadan RF should concern both clinicians and dietician nutritionists. Nevertheless, studies with larger sample size and/or long-term follow-up are warranted before reaching definite conclusions about the effects of RF on human health.

Indexed as

DyslipidemiasFastingAnimalsCalciumCholesterolDairy ProductsFerritinsGlucoseHemoglobinsHumansIronLipoproteins, HDLReligionTriglyceridesVitamin B 12CalciumCholesterolFerritinsGlucoseHemoglobinsIronLipoproteins, HDLTriglyceridesVitamin B 12

Identifiers

PMID34853413
OpenAlexW3216075390

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.