Evidence map›Paper›PMID 34853411›Full record

ReviewNature reviews. Rheumatology2022

Global epidemiology of vasculitis.

Richard A Watts, Gulen Hatemi, Jane C Burns, Aladdin J Mohammad

2 registry-linked trialsOpen access · bronzeAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Nature reviews. Rheumatology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 179 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
179citing papers in PubMed, 11 pooled it
28.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06757426 not yet recruitingnot on this mapstarted 2025, after this paper: background citation

Prospective Observational Study Evaluating the Safety and Efficacy of Immunomodulatory Therapies in Refractory Inflammatory and Autoimmune Diseases

TypeobservationalSponsorGroupe français d'étude des Maladies Inflammatoires de loeilRan2025 to 2028Enrolled80ConditionsAutoimmune Diseases, Inflammatory Diseases
NCT07354503 not yet recruitingnot on this mapstarted 2026, after this paper: background citation

The Efficacy and Safety of Telitacicept in the Treatment of Pediatric IgA Vasculitis-Associated Nephritis: A Multicenter Clinical Study

Typeobservational_patient_registrySponsorThe Children's Hospital of Zhejiang University School of MedicineRan2026 to 2028Enrolled300ConditionsIgAVN, IgA VasculitisArmsCollect clinical data from the patients., This study exclusively prospectively collected clinical data from the patients and did not involve any therapeutic interventions
3 · Its place in the literature

Who cites it

179 citing papers in PubMed, 11 syntheses or guidelines pooled it, 313 citations in OpenAlex.

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  13. Rare vasculitis types and obstetric and neonatal outcomes - A population-based study.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026
    Article
  14. Review
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  19. [Vasculitides and anti-GBM disease].Innere Medizin (Heidelberg, Germany) · 2026
    Article
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119 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 4 countries.

Richard A WattsNorwich Medical School, University of East Anglia, Norwich, UK. drwattsrheumatology@gmail.com.ORCID http://orcid.org/0000-0002-2846-4769
Gulen HatemiDepartment of Internal Medicine, Division of Rheumatology and Behçet's Disease Research Centre, Istanbul University-Cerrahpaşa, Istanbul, Turkey.
Jane C BurnsDepartment of Pediatrics, University of California San Diego, La Jolla, CA, USA.
Aladdin J MohammadDepartment of Clinical Sciences, Division of Rheumatology, Lund University and Department of Rheumatology, Skåne University Hospital, Lund, Sweden.ORCID http://orcid.org/0000-0002-7169-6936
Istanbul University-Cerrahpaşa · TRLund University · SEUniversity of California San Diego · USUniversity of East Anglia · GB

Funding

Medical Research Council MR/N011775/1
6 · The paper itself

Abstract

The many forms of vasculitis are characterized by inflammation of blood vessels, leading to potentially long-term sequelae including vision loss, aneurysm formation and kidney failure. Accurate estimation of the incidence and prevalence has been hampered by the absence of reliable diagnostic criteria and the rarity of these conditions; however, much progress has been made over the past two decades, although data are still lacking from many parts of the world including the Indian subcontinent, China, Africa and South America. Giant cell arteritis occurs in those aged 50 years and over and seems to mainly affect persons of northern European ancestry, whereas Takayasu arteritis occurs mainly in those aged under 40 years. By contrast, Kawasaki disease mainly occurs in children aged under 5 years and is most common in children of Asian ancestry, and IgA vasculitis occurs in children and adolescents. Although much less common than giant cell arteritis, the different forms of antineutrophil cytoplasmic antibody-associated vasculitis are being increasingly recognized in most populations and occur more frequently with increasing age. Behçet syndrome occurs most commonly along the ancient silk road between Europe and China. Much work needs to be done to better understand the influence of ethnicity, geographical location, environment and social factors on the development of vasculitis.

Indexed as

Global HealthVasculitisHumans

Identifiers

PMID34853411
PMCPMC8633913
OpenAlexW3217556094

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.