Evidence map›Paper›PMID 34853401›Full record

ArticleScientific reports2021

Artificial intelligence-based automatic assessment of lower limb torsion on MRI.

Justus Schock, Daniel Truhn, Darius Nürnberger, Stefan Conrad, Marc Sebastian Huppertz, Sebastian Keil, Christiane Kuhl, Dorit Merhof, Sven Nebelung

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

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  7. Computed tomography-based automated 3D measurement of femoral version: Validation against standard 2D measurements in symptomatic patients.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Justus Schock *Department of Diagnostic and Interventional Radiology, University Hospital Düsseldorf, Düsseldorf, Germany.
Daniel Truhn *Department of Diagnostic and Interventional Radiology, Aachen University Hospital, Pauwels Street 30, 52074, Aachen, Germany.
Darius NürnbergerInstitute of Imaging and Computer Vision, RWTH University Aachen, Aachen, Germany.
Stefan ConradInstitute of Informatics, Heinrich Heine University, Düsseldorf, Germany.
Marc Sebastian HuppertzDepartment of Diagnostic and Interventional Radiology, Aachen University Hospital, Pauwels Street 30, 52074, Aachen, Germany.
Sebastian KeilDepartment of Diagnostic and Interventional Radiology, Aachen University Hospital, Pauwels Street 30, 52074, Aachen, Germany.
Christiane KuhlDepartment of Diagnostic and Interventional Radiology, Aachen University Hospital, Pauwels Street 30, 52074, Aachen, Germany.
Dorit MerhofInstitute of Imaging and Computer Vision, RWTH University Aachen, Aachen, Germany.
Sven NebelungDepartment of Diagnostic and Interventional Radiology, Aachen University Hospital, Pauwels Street 30, 52074, Aachen, Germany. snebelung@ukaachen.de.
Universitätsklinikum Aachen · DEDüsseldorf University Hospital · DEHeinrich Heine University Düsseldorf · DERWTH Aachen University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Abnormal torsion of the lower limbs may adversely affect joint health. This study developed and validated a deep learning-based method for automatic measurement of femoral and tibial torsion on MRI. Axial T2-weighted sequences acquired of the hips, knees, and ankles of 93 patients (mean age, 13 ± 5 years; 52 males) were included and allocated to training (n = 60), validation (n = 9), and test sets (n = 24). A U-net convolutional neural network was trained to segment both femur and tibia, identify osseous anatomic landmarks, define pertinent reference lines, and quantify femoral and tibial torsion. Manual measurements by two radiologists provided the reference standard. Inter-reader comparisons were performed using repeated-measures ANOVA, Pearson's r, and the intraclass correlation coefficient (ICC). Mean Sørensen-Dice coefficients for segmentation accuracy ranged between 0.89 and 0.93 and erroneous segmentations were scarce. Ranges of torsion as measured by both readers and the algorithm on the same axial image were 15.8°-18.0° (femur) and 33.9°-35.2° (tibia). Correlation coefficients (ranges, .968 ≤ r ≤ .984 [femur]; .867 ≤ r ≤ .904 [tibia]) and ICCs (ranges, .963 ≤ ICC ≤ .974 [femur]; .867 ≤ ICC ≤ .894 [tibia]) indicated excellent inter-reader agreement. Algorithm-based analysis was faster than manual analysis (7 vs 207 vs 230 s, p < .001). In conclusion, fully automatic measurement of torsional alignment is accurate, reliable, and sufficiently fast for clinical workflows.

Indexed as

Artificial IntelligenceAdolescentAdultAlgorithmsChildChild, PreschoolFemaleHumansLower Extremity Deformities, CongenitalMagnetic Resonance ImagingMaleNeural Networks, ComputerTorsion Abnormality

Identifiers

PMID34853401
PMCPMC8636587
OpenAlexW3217788396

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.