Evidence map›Paper›PMID 34853392›Full record

ArticleScientific reports2021

Characterization of a G-quadruplex from hepatitis B virus and its stabilization by binding TMPyP4, BRACO19 and PhenDC3.

Orsolya Réka Molnár, András Végh, Judit Somkuti, László Smeller

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 22 citations in OpenAlex.

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  14. Pressure Tuning Studies of Four-Stranded Nucleic Acid Structures.International journal of molecular sciences · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Orsolya Réka Molnár *Department of Biophysics and Radiation Biology, Semmelweis University, Budapest, 1094, Hungary.
András Végh *Department of Biophysics and Radiation Biology, Semmelweis University, Budapest, 1094, Hungary.
Judit SomkutiDepartment of Biophysics and Radiation Biology, Semmelweis University, Budapest, 1094, Hungary.
László SmellerDepartment of Biophysics and Radiation Biology, Semmelweis University, Budapest, 1094, Hungary. smeller.laszlo@med.semmelweis-univ.hu.
Semmelweis University · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Specific guanine rich nucleic acid sequences can form non-canonical structures, like the four stranded G-quadruplex (GQ). We studied the GQ-forming sequence (named HepB) found in the genome of the hepatitis B virus. Fluorescence-, infrared- and CD-spectroscopy were used. HepB shows a hybrid form in presence of K

Indexed as

G-QuadruplexesAcridinesDNAFused-Ring CompoundsGenome, ViralHepatitis B virusLigandsPorphyrinsThermodynamicsAcridinesBRACO-19DNAFused-Ring CompoundsLigandsPhenDC3Porphyrinstetra(4-N-methylpyridyl)porphine

Identifiers

PMID34853392
PMCPMC8636512
OpenAlexW3216008167

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.