Evidence map›Paper›PMID 34853170›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2021

Tryptophan metabolism and bacterial commensals prevent fungal dysbiosis in

Katarzyna W Wolinska, Nathan Vannier, Thorsten Thiergart, Brigitte Pickel, Sjoerd Gremmen, Anna Piasecka, Mariola Piślewska-Bednarek, Ryohei Thomas Nakano, Youssef Belkhadir, Paweł Bednarek and 1 more

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 2 pooled it
12.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 2 syntheses or guidelines pooled it, 79 citations in OpenAlex.

  1. Pooled it
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  13. Dynamic shifts in plant-microbe relationships.Plant biotechnology (Tokyo, Japan) · 2025
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  20. Embracing complexity in plant-microbiome systems.Environmental microbiology reports · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 3 countries.

Katarzyna W WolinskaDepartment of Plant Microbe Interactions, Max Planck Institute for Plant Breeding Research, 50829 Cologne, Germany.
Nathan VannierDepartment of Plant Microbe Interactions, Max Planck Institute for Plant Breeding Research, 50829 Cologne, Germany.
Thorsten ThiergartDepartment of Plant Microbe Interactions, Max Planck Institute for Plant Breeding Research, 50829 Cologne, Germany.
Brigitte PickelDepartment of Plant Microbe Interactions, Max Planck Institute for Plant Breeding Research, 50829 Cologne, Germany.
Sjoerd GremmenDepartment of Plant Microbe Interactions, Max Planck Institute for Plant Breeding Research, 50829 Cologne, Germany.ORCID 0000-0002-0107-1623
Anna PiaseckaInstitute of Bioorganic Chemistry, Polish Academy of Sciences, 61-704 Poznań, Poland.
Mariola Piślewska-BednarekInstitute of Bioorganic Chemistry, Polish Academy of Sciences, 61-704 Poznań, Poland.
Ryohei Thomas NakanoDepartment of Plant Microbe Interactions, Max Planck Institute for Plant Breeding Research, 50829 Cologne, Germany.ORCID 0000-0001-5973-2300
Youssef BelkhadirGregor Mendel Institute, Austrian Academy of Sciences, Vienna Biocenter, 1030 Vienna, Austria.ORCID 0000-0001-7149-7139
Paweł BednarekInstitute of Bioorganic Chemistry, Polish Academy of Sciences, 61-704 Poznań, Poland.ORCID 0000-0002-3064-7775
Stéphane HacquardDepartment of Plant Microbe Interactions, Max Planck Institute for Plant Breeding Research, 50829 Cologne, Germany; hacquard@mpipz.mpg.de.ORCID 0000-0003-2293-3525
Max Planck Institute for Plant Breeding Research · DEInstitute of Bioorganic Chemistry, Polish Academy of Sciences · PLCluster of Excellence on Plant Sciences · DEGregor Mendel Institute of Molecular Plant Biology · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In nature, roots of healthy plants are colonized by multikingdom microbial communities that include bacteria, fungi, and oomycetes. A key question is how plants control the assembly of these diverse microbes in roots to maintain host-microbe homeostasis and health. Using microbiota reconstitution experiments with a set of immunocompromised

Indexed as

ArabidopsisArabidopsis ProteinsBacteriaDysbiosisFungiMicrobiotaMycosesOomycetesPlant DevelopmentPlant RootsSoil MicrobiologySymbiosisTryptophanArabidopsis ProteinsTryptophanmicrobial homeostasismicrobial interactionsplant holobiontplant innate immunityroot microbiome

Identifiers

PMID34853170
PMCPMC8670527
OpenAlexW3217093153

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.