Evidence map›Paper›PMID 34852838›Full record

ArticleCanine medicine and genetics2021

The effect of inbreeding, body size and morphology on health in dog breeds.

Danika Bannasch, Thomas Famula, Jonas Donner, Heidi Anderson, Leena Honkanen, Kevin Batcher, Noa Safra, Sara Thomasy, Robert Rebhun

Abstract read
In one paragraph

Article in Canine medicine and genetics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed.

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  8. Genotypic and phenotypic consequences of domestication in dogs.bioRxiv : the preprint server for biology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Danika BannaschDepartment of Population Health and Reproduction, School of Veterinary Medicine, University of California-Davis, Davis, CA, 95616, USA. dlbannasch@ucdavis.edu.ORCID http://orcid.org/0000-0002-7614-7207
Thomas FamulaDepartment of Animal Science, University of California-Davis, Davis, CA, 95616, USA.
Jonas DonnerWisdom Health Genetics, Kinship, FI-00290, Helsinki, Finland.
Heidi AndersonWisdom Health Genetics, Kinship, FI-00290, Helsinki, Finland.
Leena HonkanenWisdom Health Genetics, Kinship, FI-00290, Helsinki, Finland.
Kevin BatcherDepartment of Population Health and Reproduction, School of Veterinary Medicine, University of California-Davis, Davis, CA, 95616, USA.
Noa SafraDepartment of Population Health and Reproduction, School of Veterinary Medicine, University of California-Davis, Davis, CA, 95616, USA.
Sara ThomasyDepartment of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California-Davis, Davis, CA, 95616, USA.
Robert RebhunDepartment of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California-Davis, Davis, CA, 95616, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDog breeds are known for their distinctive body shape, size, coat color, head type and behaviors, features that are relatively similar across members of a breed. Unfortunately, dog breeds are also characterized by distinct predispositions to disease. We explored the relationships between inbreeding, morphology and health using genotype based inbreeding estimates, body weight and insurance data for morbidity.

resultsThe average inbreeding based on genotype across 227 breeds was F

conclusionsIn this study, body size and inbreeding along with deleterious morphologies contributed to increases in necessary health care in dogs.

Indexed as

CanineGeneticInheritedMorbidityMortality

Identifiers

PMID34852838
PMCPMC8638537

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.