ArticleBMC geriatrics2021
Association between change in handgrip strength and cognitive function in Korean adults: a longitudinal panel study.
Article in BMC geriatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Associations between independent or concurrent decline in upper and lower limb strength and cognitive impairment.BMC geriatrics · 2026Article
- Article
- Association of sensory and motor impairments with dementia: a cross-sectional analysis in US older adults.BMC geriatrics · 2025Article
- Physical fitness and incident mild cognitive impairment: a systematic review.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2025Review
- Cumulative handgrip strength and longitudinal changes in cognitive function and daily functioning among people aged 50 years and older: evidence from two longitudinal cohort studies.Archives of public health = Archives belges de sante publique · 2025Article
- Interplay of Physical Activity, Muscle Strength, and Depression in Cognitive Impairment among Korean Older Adults: A Cross-sectional Study.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2025Article
- Cognitive cerebellum dominates motor cerebellum in functional decline of older adults with mild cognitive impairment.PloS one · 2025Article
- Handgrip strength is associated with cognitive function in older patients with stage 3-5 chronic kidney disease: results from the NHANES.Scientific reports · 2024Article
- The Grip Strength Loss Rate and the Subsequent Cognitive Decline Rate in Older Adults: The Moderating Role of Social Isolation.Innovation in aging · 2024Article
- A Metamaterial Computational Multi-Sensor of Grip-Strength Properties with Point-of-Care Human-Computer Interaction.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023Article
- One-year change in sarcopenia was associated with cognitive impairment among haemodialysis patients.Journal of cachexia, sarcopenia and muscle · 2023Article
- Nativity differences in the relationship between handgrip strength and cognitive impairment in older Mexican Americans over 20 years of follow-up.Archives of gerontology and geriatrics · 2023Article
- Marital transition and cognitive function among older adults: the korean Longitudinal Study of Aging (2006-2020).BMC geriatrics · 2022Article
- Association between changes in handgrip strength and depression in Korean adults: a longitudinal panel study.Scientific reports · 2022Article
- Handgrip Strength and Cognitive Function among Elderly Koreans: Insights from the Korean Longitudinal Study of Ageing.International journal of environmental research and public health · 2022Article
- Handgrip strength but not SARC-F score predicts cognitive impairment in older adults with multimorbidity in primary care: a cohort study.BMC geriatrics · 2022Article
- Mediating effect of lower extremity muscle strength on the relationship between mobility and cognitive function in Chinese older adults: A cross-sectional study.Frontiers in aging neuroscience · 2022Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMuscular function, such as handgrip strength, has been suggested as an associated factor for cognitive impairment. This study investigated the association between temporal change in handgrip strength and cognitive function using longitudinal, nationwide data from Korean older adults.
methodsOur study used data from the Korean Longitudinal Study of Aging (KLoSA). The analysis covered 6696 participants who had taken the handgrip strength test and Mini-Mental State Examination (MMSE) from 2006 to 2018. We adopted general estimating equations to assess the temporal effect of handgrip strength change on cognitive function.
resultsAfter adjusting for covariates, we observed an association between handgrip strength and low MMSE scores (β = - 0.3142 in men, β = - 0.2685 in women). Handgrip strength as a continuous variable was positively correlated with MMSE scores after adjustment (β = 0.0293 in men, β = 0.0347 in women). The group with decreased handgrip strength over time also showed greater odds for mild cognitive impairment (OR = 1.23, 95%CI = 1.05-1.27 in men, OR = 1.15, 95%CI = 1.05-1.27 in women) and dementia (OR = 1.393, 95%CI = 1.18-1.65 in men, OR = 1.19, 95%CI = 1.08-1.32 in women).
conclusionsThis study identified the relationship between handgrip strength change and cognitive function among South Korean adults. According to our large, longitudinal sample, decreasing handgrip strength was associated with decline in cognitive function.
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