ArticleEuropean review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity2021
Effect of hypoxic conditioning on functional fitness, balance and fear of falling in healthy older adults: a randomized controlled trial.
Article in European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04281264 (Strength Training in Hypoxia to Improve Bone and Cardiovascular Health of Elderly), which is not on this map. Cited by 10 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Strength Training in Hypoxia to Improve Bone and Cardiovascular Health of Elderly
Who cites it
10 citing papers in PubMed, 5 syntheses or guidelines pooled it, 15 citations in OpenAlex.
- The effects of hypoxic versus normoxic exercise training on body composition, cardiometabolic health markers, and functional performance in adults: a systematic review and meta-analysis.BMC sports science, medicine & rehabilitation · 2026Pooled it
- Combined training in hypoxic environments improves cardiometabolic health in older adults: a systematic review and meta-analysis of randomized controlled trials.Frontiers in medicine · 2025Pooled it
- Effect of Hypoxia Conditioning on Body Composition in Middle-Aged and Older Adults: A Systematic Review and Meta-Analysis.Sports medicine - open · 2023Pooled it
- Effects of Intermittent Normobaric Hypoxia on Health-Related Outcomes in Healthy Older Adults: A Systematic Review.Sports medicine - open · 2023Pooled it
- The role of resistance exercise training for improving cardiorespiratory fitness in healthy older adults: a systematic review and meta-analysis.Age and ageing · 2022Pooled it
- Comparative effects of hypoxic exercise training modalities on cardiometabolic health: A systematic review and network meta-analysis.iScience · 2025Article
- The Effects of Exercise Intervention in Older Adults With and Without Sarcopenia: A Systematic Review.Sports (Basel, Switzerland) · 2025Review
- Effectiveness of exercise prescription variables to reduce fall risk among older adults: a meta-analysis.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2025Review
- Association between Gait Speed and Balance Disorders in Older Adults from 12 High Andean Peruvian Communities, 2013-2019.Annals of geriatric medicine and research · 2024Article
- Editorial: Hypoxia as a therapeutic tool in search of healthy aging.Frontiers in physiology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundHypoxic conditioning has been proposed as a new tool to mitigate the sarcopenia and enhance health-related function, but decrements in standing balance have been observed during hypoxia exposure. The aim of the study was to evaluate the effect of a hypoxic conditioning training on functional fitness, balance and fear of falling in healthy older adults.
methodsA total of 54 healthy older adults (aged 65-75 years), who voluntarily participated in the study, were randomly divided into three groups: the control group (CON), the normoxia training group (NT) that performed strength training in normoxia, and the hypoxia training group (HT) that trained under moderate hypoxic conditions at a simulated altitude of 2500 m asl. The training programme that was performed during 24 weeks was similar in both experimental groups and consisted of a full-body workout with elastic bands and kettlebells (three sets × 12-15 reps). The Senior Fitness Test (SFT), the Single Leg Stance test (SLS) and the Short Falls Efficacy Scale-International (FES-I) were assessed before and after the intervention.
resultsResults showed that after training, either in normoxia or in hypoxia, the participants increased upper and lower body strength, and the aerobic endurance, and decreased the fear of falling.
conclusionsThe moderate hypoxic conditioning seems to be a useful tool to increase the functional capacity in healthy older adults without observing a decline in balance.
trial registrationClinicalTrials.gov NCT04281264 . Registered February 9, 2019-Retrospectively registered.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.