Evidence map›Paper›PMID 34852062›Full record

ArticleArquivos brasileiros de oftalmologia

Structural alterations of the choroid evaluated using enhanced depth imaging optical coherence tomography in patients with coronavirus disease.

Özkan Kocamış, Emine Temel, Lokman Hızmalı, Nazife Aşıkgarip, Kemal Örnek, Fikriye Milletli Sezgin

Open access · diamondAbstract read
In one paragraph

Article in Arquivos brasileiros de oftalmologia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. COVID-19 Associated Choroidopathy.Journal of clinical medicine · 2021
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Özkan KocamışDepartment of Opthalmology, Kırşehir Ahi Evran University School of Medicine, Kırşehir, Turkey.
Emine TemelDepartment of Opthalmology, Kırşehir Ahi Evran Training and Research Hospital, Kırşehir, Turkey.ORCID 0000-0001-6302-9175
Lokman HızmalıDepartment of Infectious Disease and Clinical Microbiology, Kırşehir Ahi Evran University School of Medicine, Kırşehir, Turkey.
Nazife AşıkgaripDepartment of Opthalmology, Kırşehir Ahi Evran Training and Research Hospital, Kırşehir, Turkey.
Kemal ÖrnekDepartment of Opthalmology, Kırşehir Ahi Evran University School of Medicine, Kırşehir, Turkey.ORCID 0000-0002-7745-1892
Fikriye Milletli SezginDepartment of Medical Microbiology, Kırşehir Ahi Evran University School of Medicine, Kırşehir, Turkey.
Ahi Evran University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo assess choroidal changes using enhanced depth imaging optical coherence tomography in coronavirus disease (COVID-19).

methodsThirty-two patients with moderate COVID-19 and 34 healthy subjects were included in the study. Choroidal thickness was measured at 3 points as follows: at the subfovea, 1500 mm nasal to the fovea, and 1500 mm temporal to the fovea. The total choroidal area, luminal area, stromal area, and choroidal vascular index were measured with Image-J. All the measurements were performed during the disease and at 4 months after remission.

resultsIn the patient group, the subfoveal, nasal, and temporal choroidal thicknesses were decreased as compared with those in the controls, but without statistically significant differences (p=0.534, p=0.437, and p=0.077, respectively). The mean total choroidal, stromal, and luminal areas and choroidal vascular index were statistically significantly decreased in the patient group (p<0.001, p=0.001, p=0.001, and p=0.003; respectively). At 4 months after remission, the choroidal structural parameters and choroidal vascular index revealed statistically significant increases as compared with the baseline measurements in the patients with COVID-19 (all p<0.001 and p=0.047, respectively).

conclusionThe choroidal vascular and stromal parameters showed significant transient decreases during the disease course of COVID-19.

Indexed as

COVID-19Tomography, Optical CoherenceChoroidFovea CentralisHumansOrgan Size

Identifiers

PMID34852062
PMCPMC11826795
OpenAlexW3213585343

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.