ArticleAJR. American journal of roentgenology2022
Paramagnetic Rim Lesions in Multiple Sclerosis: Comparison of Visualization at 1.5-T and 3-T MRI.
Registry-linked trialOpen access · greenAbstract read
In one paragraph
Article in AJR. American journal of roentgenology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07705581 (Validation and Standardization of Paramagnetic Rim Lesion), which is not on this map. Cited by 33 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
5.8field-weighted citation impact, top 3% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Validation and Standardization of Paramagnetic Rim Lesion (PRL) Identification in Multiple Sclerosis Across MAGNIMS Centers - From Scientific Setting Towards Clinical Applicability
Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it, 62 citations in OpenAlex.
- Reliability of paramagnetic rim lesion classification on quantitative susceptibility mapping (QSM) in people with multiple sclerosis: Single-site experience and systematic review.Multiple sclerosis and related disorders · 2023Pooled it
- AI-Powered Gradient Echo Plural Contrast Imaging (AI-GEPCI)-A Comprehensive Neurological Protocol From a Single MRI Scan.Journal of magnetic resonance imaging : JMRI · 2026Article
- Iron accumulation in the corpus callosum: a quantitative MRI study in relapsing-remitting multiple sclerosis.Irish journal of medical science · 2026Article
- Central Vein Sign and Paramagnetic Rim Lesions in Patients with Relapsing-Remitting Multiple Sclerosis: An Assessment of Prevalence and Anatomical Location.Neurology international · 2026Article
- Filtered-phase imaging versus susceptibility-weighted imaging for paramagnetic rim lesion detection in multiple sclerosis: A head-to-head comparison.Multiple sclerosis (Houndmills, Basingstoke, England) · 2026Article
- AI-powered Gradient Echo Plural Contrast Imaging (AI-GEPCI) - a Comprehensive Multiparametric Neurological Protocol from a Single MRI Scan.medRxiv : the preprint server for health sciences · 2026Article
- Investigating the Frequency and Outcome of Central Vein Sign and Paramagnetic Rim Lesions in Children With MOGAD.Neurology · 2026Article
- Hidden Pitfall in Multiple Sclerosis Imaging: How Standard Susceptibility-Weighted Imaging (SWI) May Miss Paramagnetic Rim Lesions.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2026Article
- Updates in Multiple Sclerosis Imaging.Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2025Review
- Frequency and Diagnostic Implications of Paramagnetic Rim Lesions in People Presenting for Diagnosis to a Multiple Sclerosis Clinic.Neurology · 2025Observational
- Paramagnetic rim lesion formation is predicted by the initial gadolinium-enhancing lesion diameter.Multiple sclerosis (Houndmills, Basingstoke, England) · 2025Article
- Paramagnetic rim lesions are highly specific for multiple sclerosis in real-world data.Brain communications · 2025Article
- Paramagnetic rim lesions are associated with inner retinal layer thinning and progression independent of relapse activity in multiple sclerosis.European journal of neurology · 2025Article
- The role of microglia in multiple sclerosis: implications for treatment with Bruton's tyrosine kinase inhibitors.Frontiers in immunology · 2025Review
- Imaging Outcomes for Phase 2 Trials Targeting Compartmentalized Inflammation.Multiple sclerosis (Houndmills, Basingstoke, England) · 2024Review
- Predicting multiple sclerosis disease progression and outcomes with machine learning and MRI-based biomarkers: a review.Journal of neurology · 2024Review
- Imaging chronic active lesions in multiple sclerosis: a consensus statement.Brain : a journal of neurology · 2024Review
- Multiparametric Characterization and Spatial Distribution of Different MS Lesion Phenotypes.AJNR. American journal of neuroradiology · 2024Article
- New Imaging Markers in Multiple Sclerosis and Related Disorders: Smoldering Inflammation and the Central Vein Sign.Neuroimaging clinics of North America · 2024Review
- Central Vein Sign and Paramagnetic Rim Lesions: Susceptibility Changes in Brain Tissues and Their Implications for the Study of Multiple Sclerosis Pathology.Diagnostics (Basel, Switzerland) · 2024Review
Corrections and comments
- Commented on by
Authors and funding
3 authors at 1 institution in 1 country.
Christopher C HemondDepartment of Neurology, University of Massachusetts Medical Center, 55 Lake Ave N, Worcester, MA 01655.
Daniel S ReichTranslational Neuroradiology Section, Division of Neuroimmunology and Neurovirology, National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD.
Sathish K DundamadappaDepartment of Radiology, University of Massachusetts Medical School, Worcester, MA.
University of Massachusetts Chan Medical School · US
Funding
Multimodal MRI in Multiple SclerosisZIANS003119 · NINDS · NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE · PI REICH, DANIEL · 2010 to 2025
$53.4MUniversity of Massachusetts Center for Clinical and Translational ScienceKL2TR001455 · NCATS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI KIEFE, CATARINA I. · 2015 to 2024
$5.0MUniversity of Massachusetts Center for Clinical and Translational ScienceTL1TR001454 · NCATS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI LEWIS, BRIAN C · 2015 to 2024
$3.6MMRI Paramagnetic Rim Lesions as Biomarkers and Agents of Neurodegeneration in Multiple SclerosisK23NS126718 · NINDS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI Christopher C. Hemond · 2022 to 2026
$1.0MNCATS NIH HHS KL2 TR001455NCATS NIH HHS TL1 TR001454NINDS NIH HHS K23 NS126718
Abstract
PubMed holds no abstract for this paper.
Indexed as
Multiple SclerosisBrainFemaleHumansInflammationMagnetic Resonance ImagingMaleMiddle AgedRetrospective Studies1.5 T3 Tchronic active lesionfiltered phaseiron rim lesionmultiple sclerosisparamagnetic rim lesionsusceptibility-weighted imagingT2
Identifiers
What OpenQuestion holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
NCT07705581ClinicalTrials.gov
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.