ArticleScience translational medicine2021
Dynamic PET-facilitated modeling and high-dose rifampin regimens for
Open access · greenAbstract read
In one paragraph
Article in Science translational medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 27 citations in OpenAlex.
- Rifampicin in Osteoarticular Infections: A Comprehensive Review of Current Evidence.Antibiotics (Basel, Switzerland) · 2026Review
- Radiolabeled Antimicrobials for Infection Imaging: A Scoping Review.International journal of molecular sciences · 2026Article
- Recent advances in multimodal imaging of infections: research highlights using Nuclear-Optical imaging.European journal of nuclear medicine and molecular imaging · 2026Review
- Chemically modified and inactivated bacteria enable intra-biofilm drug delivery and long-term immunity against implant infections.Nature biomedical engineering · 2026Article
- Pitaya‑inspired compartmentalized microspheres with natural tannic acid-copper coating orchestrate smart release of ions and multi-drugs for synergistic treatment of infected bone defects.Regenerative biomaterials · 2026Article
- Application of Nuclear Medicine Techniques in Musculoskeletal Infection: Current Trends and Future Prospects.Journal of clinical medicine · 2024Review
- Linezolid does not improve bactericidal activity of rifampin-containing first-line regimens in animal models of TB meningitis.International journal of antimicrobial agents · 2024Article
- Is Imaging Bacteria with PET a Realistic Option or an Illusion?Diagnostics (Basel, Switzerland) · 2023Review
- New Approaches for Imaging Bacteria.Seminars in nuclear medicine · 2023Review
- Current and Future Applications of Fluorescence Guidance in Orthopaedic Surgery.Molecular imaging and biology · 2023Review
- Systemic rifampicin shows accretion to locally implanted hydroxyapatite particles in a rat abdominal muscle pouch model.Journal of bone and joint infection · 2023Article
- Antibiotic-Derived Radiotracers for Positron Emission Tomography: Nuclear or "Unclear" Infection Imaging?Angewandte Chemie (International ed. in English) · 2022Review
- High-dose rifampin improves bactericidal activity without increased intracerebral inflammation in animal models of tuberculous meningitis.The Journal of clinical investigation · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
21 authors at 4 institutions in 1 country.
Oren GordonDivision of Infectious Diseases, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.ORCID 0000-0002-3159-8426
Donald E LeeCenter for Translational Medicine, University of Maryland School of Pharmacy, Baltimore, MD 21201, USA.ORCID 0000-0002-4267-7699
Bessie LiuW. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD 21205, USA.
Brooke LangevinCenter for Translational Medicine, University of Maryland School of Pharmacy, Baltimore, MD 21201, USA.
Alvaro A OrdonezDivision of Infectious Diseases, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.ORCID 0000-0002-8571-0655
Dustin A DikemanDepartment of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.ORCID 0000-0003-1716-1479
Babar ShafiqDepartment of Orthopedic Surgery, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.ORCID 0000-0002-9204-0477
John M ThompsonDepartment of Orthopedic Surgery, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.ORCID 0000-0002-7981-2882
Paul D SponsellerDepartment of Orthopedic Surgery, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.ORCID 0000-0003-2934-6374
Kelly FlavahanDivision of Infectious Diseases, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
Martin A LodgeDivision of Nuclear Medicine and Molecular Imaging, Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.ORCID 0000-0003-0922-6519
Steven P RoweDivision of Nuclear Medicine and Molecular Imaging, Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.ORCID 0000-0003-2897-4694
Robert F DannalsDivision of Nuclear Medicine and Molecular Imaging, Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.ORCID 0000-0002-5483-5914
Camilo A Ruiz-BedoyaDivision of Infectious Diseases, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.ORCID 0000-0002-0653-4244
Timothy D ReadDivision of Infectious Diseases, Department of Medicine, Emory University, Atlanta, GA 30322, USA.ORCID 0000-0001-8966-9680
Charles A PeloquinInfectious Disease Pharmacokinetics Laboratory, Pharmacotherapy and Translational Research, University of Florida College of Pharmacy, Gainesville, FL 32610, USA.ORCID 0000-0001-9002-7052
Nathan K ArcherDepartment of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.ORCID 0000-0002-8212-8985
Lloyd S MillerDepartment of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.ORCID 0000-0002-8332-2210
Kimberly M DavisW. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD 21205, USA.ORCID 0000-0003-1870-3137
Jogarao V S GobburuCenter for Translational Medicine, University of Maryland School of Pharmacy, Baltimore, MD 21201, USA.ORCID 0000-0002-8348-4295
Sanjay K JainDivision of Infectious Diseases, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.ORCID 0000-0001-9620-7070
Johns Hopkins University · USUniversity of Maryland, Baltimore · USAmerican Association of Colleges of Pharmacy · USEmory University · US
Funding
Research Training in Pediatric Infectious DiseasesT32AI052071 · NIAID · JOHNS HOPKINS UNIVERSITY · PI AARON M MILSTONE · 2002 to 2026
$5.2MMeasuring Intralesional Drug Exposures in Cavitary TB using Noninvasive In Vivo PET ImagingR01AI153349 · NIAID · JOHNS HOPKINS UNIVERSITY · PI JAIN, SANJAY · 2020 to 2024
$3.8MNovel Imaging Tracers for Rapid and Noninvasive Assessment of Bacterial InfectionR01EB020539 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI JAIN, SANJAY · 2014 to 2018
$3.6MDevelopment of 11C-PABA as a bacteria-specific imaging agent for spinal infectionsR01EB025985 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JAIN, SANJAY, WILSON, DAVID M · 2018 to 2021
$2.7MMolecular Imaging for Pulmonary Infections and InflammationR01HL131829 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI JAIN, SANJAY · 2016 to 2018
$2.2MIL-36 responses in Staphylococcus aureus driven skin inflammationR01AR073665 · NIAMS · JOHNS HOPKINS UNIVERSITY · PI ARCHER, NATHAN K. · 2018 to 2022
$1.8MSTAT3-mediated immunity to Staphylococcus aureus in skinR01AR069502 · NIAMS · JOHNS HOPKINS UNIVERSITY · PI ARCHER, NATHAN K. · 2016 to 2020
$1.8MNHLBI NIH HHS R01 HL131829NIAID NIH HHS R01 AI153349NIAID NIH HHS T32 AI052071NIAMS NIH HHS R01 AR069502NIAMS NIH HHS R01 AR073665NIBIB NIH HHS R01 EB020539NIBIB NIH HHS R01 EB025985
Abstract
PubMed holds no abstract for this paper.
Indexed as
RifampinStaphylococcal InfectionsAnimalsAnti-Bacterial AgentsHumansMiceMicrobial Sensitivity TestsPositron-Emission TomographyStaphylococcus aureusAnti-Bacterial AgentsRifampin
Identifiers
What OpenQuestion holds
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Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.