Evidence map›Paper›PMID 34850963›Full record

ArticleMolecular medicine reports2022

Long non‑coding RNA MBI‑52 inhibits the development of liver fibrosis by regulating the microRNA‑466g/SMAD4 signaling pathway.

Yazhou Li, Peixiao Liu, Feipeng Wei

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular medicine reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Yazhou LiDepartment of Pain Intervention, Baoji High‑tech People's Hospital, Baoji, Shaanxi 721000, P.R. China.
Peixiao LiuDepartment of Cardiopulmonary Rehabilitation, Xi'an International Medical Center Hospital, Xi'an, Shaanxi 710000, P.R. China.
Feipeng WeiDepartment of Interventional Radiology, Tangdu Hospital, Air Force Military Medical University, Xi'an, Shaanxi 710038, P.R. China.
Baoji City Central Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Liver fibrosis is a wound healing response triggered by liver injury. In severe cases, it may develop into liver cirrhosis, liver cancer and liver failure. Long non‑coding RNAs (lncRNAs) play key roles in the development of liver fibrosis. The present study aimed to investigate the role of lncRNA‑MBI‑52 (lnc‑MBI‑52) in the progression of liver fibrosis. Carbon tetrachloride (CCl

Indexed as

Gene Expression RegulationAnimalsCarbon TetrachlorideHepatic Stellate CellsHumansLiver CirrhosisMaleMiceMice, Inbred C57BLMicroRNAsRNA, Long NoncodingSignal TransductionSmad4 ProteinTransforming Growth Factor beta1Carbon TetrachlorideMicroRNAsMirn466 microRNA, mouseRNA, Long NoncodingSmad4 ProteinSmad4 protein, mouseTgfb1 protein, mouseTransforming Growth Factor beta1liver fibrosislong non‑coding RNA‑MBI‑52microRNA‑466gSMAD4transforming growth factor‑β1

Identifiers

PMID34850963
PMCPMC8669687
OpenAlexW3216260314

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.