Evidence map›Paper›PMID 34850379›Full record

ArticleJournal of the American Geriatrics Society2022

Loneliness, sadness, and feelings of social disconnection in older adults during the COVID-19 pandemic.

Louisa W Holaday, Carol R Oladele, Samuel M Miller, Maria I Dueñas, Brita Roy, Joseph S Ross

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in Journal of the American Geriatrics Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06441136 (Characterizing the Impact of Presbyphonia on Social Interaction), which is not on this map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06441136 narecruitingnot on this mapstarted 2025, after this paper: background citation

Characterizing the Impact of Presbyphonia on Social Interaction

TypeinterventionalSponsorMatthew R. HoffmanRan2025 to 2026Enrolled25ConditionsPresbyphoniaArmsPhoRTE Program, University of California Los Angeles (UCLA) Loneliness Scale, Social Disconnectedness Scale, Patient Health Questionnaire 9, Aging Voice Index
3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 55 citations in OpenAlex.

  1. How Race, Gender, and Cohort Shape Social Isolation and Loneliness in Older Americans.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2026
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  4. Effects of Situational Loneliness on Mental Health and Sleep Health Outcomes among White Older Adults during the COVID-19 Pandemic.Prevention science : the official journal of the Society for Prevention Research · 2025
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  12. The Effect of COVID-19 on Dual-Eligible Beneficiaries: A Scoping Review.Journal of the American Medical Directors Association · 2023
    Article
  13. Article
  14. Pain Management in Older Adults Before and During the First Year of COVID-19 Pandemic: Prevalence, Trends, and Correlates.The journals of gerontology. Series A, Biological sciences and medical sciences · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Louisa W HoladayDivision of General Internal Medicine, Department of Medicine, Mount Sinai School of Medicine, New York, New York, USA.ORCID 0000-0002-9894-6501
Carol R OladeleSection of General Medicine, Department of Internal Medicine, Yale School of Medicine, Yale University, New Haven, Connecticut, USA.
Samuel M MillerNational Clinician Scholars Program, Yale School of Medicine, New Haven, Connecticut, USA.ORCID 0000-0001-6407-5501
Maria I DueñasDivision of General Internal Medicine, Department of Medicine, Mount Sinai School of Medicine, New York, New York, USA.
Brita RoySection of General Medicine, Department of Internal Medicine, Yale School of Medicine, Yale University, New Haven, Connecticut, USA.
Joseph S RossNational Clinician Scholars Program, Yale School of Medicine, New Haven, Connecticut, USA.
Yale University · USUCLA Medical Center · USYale New Haven Hospital · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Yale-Mayo FDA Center for Excellence in Regulatory Science and InnovationU01FD005938 · FDA · YALE UNIVERSITY · PI Joseph Solomon Ross · 2016 to 2026
$25.4M
NRSA Training CoreTL1TR001864 · NCATS · YALE UNIVERSITY · PI CANTLEY, LLOYD G, EDELMAN, E. JENNIFER · 2016 to 2025
$9.9M
Understanding hospital value: provider, hospital and community effectsR01HS022882 · AHRQ · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI HORWITZ, LEORA · 2014 to 2023
$2.9M
Research Training for the Care of Vulnerable Older Adults with Alzheimer’s Disease and Related Dementias and Other Chronic ConditionsT32AG066598 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Alex D Federman · 2020 to 2026
$2.3M
Leveraging Physician Networks to Improve Care and Outcomes for Low-Income PopulationsR01HL144644 · NHLBI · YALE UNIVERSITY · PI NDUMELE, CHIMA · 2019 to 2021
$1.6M
Medical reversals: De-implementing ineffective and unsafe treatmentsR01HS025164 · AHRQ · UNIVERSITY OF MINNESOTA · PI KARACA-MANDIC, PINAR · 2017 to 2020
$1.4M
Food insecurity and hypertension in the Eastern CaribbeanK01HL145347 · NHLBI · YALE UNIVERSITY · PI OLADELE, CAROL RENEE · 2019 to 2023
$797k
Using Participatory Systems Modeling to Understand Community Influences on Cardiovascular HealthK08HL143133 · NHLBI · YALE UNIVERSITY · PI ROY, BRITA · 2019 to 2021
$502k
Agency for Healthcare Research and Quality R01HS022882AHRQ HHS R01 HS022882AHRQ HHS R01 HS025164FDA HHS U01 FD005938Johnson and JohnsonLaura and John Arnold FoundationNational Evaluation System for Health TechnologyNCATS NIH HHS TL1 TR001864NCATS NIH HHS UL1 TR001863NHLBI NIH HHS 1K01HL145347-01A1NHLBI NIH HHS 1K08 HL1431333-01A1NHLBI NIH HHS K01 HL145347NHLBI NIH HHS K08 HL143133NHLBI NIH HHS R01 HL144644NHLBI NIH HHS R01HL144644NHLBI NIH HHS R01HS025164NIA NIH HHS T32 AG066598NIA NIH HHS T32AG066598U.S. Food and Drug Administration U01FD005938
6 · The paper itself

Abstract

backgroundPublic health measures to control the COVID-19 pandemic have led to feelings of loneliness among older adults, which, prior to COVID, has been associated with subsequent morbidity and mortality. We sought to identify differences in feelings of loneliness, sadness, and social disconnection early in the pandemic across racial groups, and possible mitigating factors.

methodsWe performed a cross-sectional analysis using the weighted nationally-representative Medicare Current Beneficiaries Survey COVID-19 supplement, collected summer 2020. We included all Medicare beneficiaries aged 65 years and older who did not respond by proxy. We examined changes in loneliness, sadness, or feelings of social disconnection. Multivariable logistic regression models accounted for sociodemographic variables, access to primary care and the internet, and history of depression or dementia.

resultsAmong 8125 beneficiaries, representative of 43.7 million Medicare beneficiaries, 22.6% reported loneliness or sadness, and 37.1% feeling socially disconnected. In fully-adjusted models, Hispanic/Latinx beneficiaries were most likely to report loneliness or sadness (OR = 1.3, CI: 1.02-1.65; p = 0.02) and Black beneficiaries were least likely to report feeling socially disconnected (OR = 0.55; CI: 0.42-0.73; p < 0.001). Internet access was associated with increased odds of both (OR = 1.29, 95 CI: 1.07-1.56; p = 0.009; and OR = 1.42, 95 CI: 1.24-1.63; p < 0.001, respectively). Access to primary care was associated with lower odds of both (OR = 0.77, 95 CI: 0.61-0.96; p = 0.02; and OR = 0.72, 95 CI: 0.61-0.87; p < 0.001).

conclusionsLoneliness, sadness, and feelings of social disconnection were common among older Medicare beneficiaries early in the COVID-19 pandemic. Differences by race/ethnicity may be driven by different living structures and social networks, and warrant further study. Policy makers and clinicians should consider facilitating connection by phone or in person, as internet access did not diminish feelings of loneliness, particularly for those living alone. Access to primary care, and tools for clinicians to address loneliness should be prioritized.

Indexed as

Social IsolationAgedCOVID-19Cross-Sectional StudiesEthnicityFemaleHumansLonelinessMaleMedicareSadnessSurveys and QuestionnairesUnited StatesInternetlonelinessprimary careracial disparitiessocial connection

Identifiers

PMID34850379
PMCPMC8896574
OpenAlexW3215015401

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.