Evidence map›Paper›PMID 34850331›Full record

SynthesisSleep & breathing = Schlaf & Atmung2022

Effects of respiratory training on obstructive sleep apnea: systematic review and meta-analysis.

Bianca Lopes Cavalcante-Leão, Cristiano Miranda de Araujo, Glória Cortz Ravazzi, Isabela Bittencourt Basso, Odilon Guariza-Filho, Karinna Veríssimo Meira Taveira, Rosane Sampaio Santos, José Stechman-Neto, Bianca Simone Zeigelboim

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Sleep & breathing = Schlaf & Atmung, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Effectiveness of aerobic exercise training in patients with obstructive sleep apnea: a systematic review and meta-analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Pooled it
  2. Trial
  3. Article
  4. Exploring Exercise Interventions for Obstructive Sleep Apnea: A Scoping Review.Journal of functional morphology and kinesiology · 2025
    Review
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Bianca Lopes Cavalcante-LeãoPostgraduate Program in Communication Disorders, Tuiuti University of Paraná, Street Sydnei Antonio Rangel Santos, 238 - Santo Inacio, Curitiba, PR, 82010-330, Brazil. bianca.leao@utp.br.ORCID 0000-0002-6170-1914
Cristiano Miranda de AraujoPostgraduate Program in Communication Disorders, Tuiuti University of Paraná, Street Sydnei Antonio Rangel Santos, 238 - Santo Inacio, Curitiba, PR, 82010-330, Brazil.ORCID 0000-0003-1325-4248
Glória Cortz RavazziPostgraduate Program in Communication Disorders, Tuiuti University of Paraná, Street Sydnei Antonio Rangel Santos, 238 - Santo Inacio, Curitiba, PR, 82010-330, Brazil.ORCID 0000-0002-6574-9878
Isabela Bittencourt BassoPostgraduate Program in Dentistry, Pontifícia Universidade Católica do Paraná, Curitiba, Paraná, Brazil.ORCID 0000-0001-9511-047X
Odilon Guariza-FilhoDepartment of Orthodontics, Pontifícia Universidade Católica do Paraná, Curitiba, Paraná, Brazil.ORCID 0000-0001-9799-1223
Karinna Veríssimo Meira TaveiraDepartment of Morphology- Center of Biosciences, Federal University of Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil.ORCID 0000-0001-6978-4083
Rosane Sampaio SantosPostgraduate Program in Communication Disorders, Tuiuti University of Paraná, Street Sydnei Antonio Rangel Santos, 238 - Santo Inacio, Curitiba, PR, 82010-330, Brazil.ORCID 0000-0001-6400-5706
José Stechman-NetoPostgraduate Program in Communication Disorders, Tuiuti University of Paraná, Street Sydnei Antonio Rangel Santos, 238 - Santo Inacio, Curitiba, PR, 82010-330, Brazil.ORCID 0000-0002-0259-2420
Bianca Simone ZeigelboimPostgraduate Program in Communication Disorders, Tuiuti University of Paraná, Street Sydnei Antonio Rangel Santos, 238 - Santo Inacio, Curitiba, PR, 82010-330, Brazil.ORCID 0000-0003-4871-2683
Universidade Tuiuti do Paraná · BRPontifícia Universidade Católica do Paraná · BRUniversidade Federal do Rio Grande do Norte · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis systematic review sought to answer the following focused question: "What are the effects of respiratory training devices on obstructive sleep apnea (OSA) outcomes in adults?"

methodsThe acronym "PICOS" was used to determine eligibility criteria, which consists of (P population) = adults with mild to moderate OSA, (I intervention) = spirometry devices or breathing exercises, (C comparison) = compared to no breathing exercises in adults (> 18 years) with mild to moderate OSA, (O outcomes) = improved sleep quality (sleep quality indexes) and improved apnea-hypopnea indexes (AHI), (S study types) = randomized, pseudo-randomized, and non-randomized clinical trials. The search was performed in the following databases: PubMed/Medline, LILACS, Scopus, Web of Science, Scopus, and Cochrane Library, in addition to gray literature through Google Scholar, Proquest, and Open Grey. The risk of bias was assessed using the Cochrane Collaboration tool. The certainty of the evidence was assessed using the GRADE tool. Meta-analyses of random effects were performed for the outcomes of interest.

resultsA total of 1171 references were found. Applying the eligibility criteria, six studies were included in qualitative synthesis. Expiratory exercises showed a decrease in the apnea-hypopnea index (AHI) when compared to baseline (MD =  - 8.4; 95% CI =  - 12.4 to - 4.4; I

conclusionResults of this meta-analysis suggests that breathing exercises lead to a measurable improvement in AHI for patients with mild to moderate OSA, as well as an improvement in sleep quality and daytime sleepiness. SYSTEMATIC REVIEW REGISTRATION: CRD42020148513 (PROSPERO).

Indexed as

Disorders of Excessive SomnolenceSleep Apnea, ObstructiveAdultBreathing ExercisesClinical Trials as TopicExerciseHumansRespiratory RateBreathing ExercisesMeta-analysisSleep apneaSpirometry

Identifiers

PMID34850331
OpenAlexW3215083820

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.