Evidence map›Paper›PMID 34850062›Full record

ArticleJournal of the National Cancer Institute2022

Cancer Microbiology.

Daniel DiMaio, Brinda Emu, Andrew L Goodman, Walther Mothes, Amy Justice

Open access · greenAbstract read
In one paragraph

Article in Journal of the National Cancer Institute, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. Review
  9. Frontiers in pharmacology · 2022
    Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Daniel DiMaioDepartment of Genetics, Yale School of Medicine, New Haven, CT, USA.ORCID 0000-0002-2060-5977
Brinda EmuYale Cancer Center, New Haven, CT, USA.
Andrew L GoodmanYale Cancer Center, New Haven, CT, USA.ORCID 0000-0001-7599-3471
Walther MothesYale Cancer Center, New Haven, CT, USA.ORCID 0000-0002-3367-7240
Amy JusticeYale Cancer Center, New Haven, CT, USA.ORCID 0000-0003-0139-5502
Yale Cancer Center · US

Funding

Yale Pathology Tissue Services Shared ResourceP30CA016359 · NCI · YALE UNIVERSITY · PI Eric P. Winer · 1985 to 2026
$85.0M
Yale SPORE in Lung Cancer (YSILC): The Biology and Personalized Treatment of Lung CancerP50CA196530 · NCI · YALE UNIVERSITY · PI Harriet M. Kluger · 2015 to 2026
$31.1M
Alcohol Associated Outcomes Among HIV+/- Aging VeteransU10AA013566 · NIAAA · YALE UNIVERSITY · PI JUSTICE, AMY CAROLINE · 2006 to 2010
$12.7M
Alcohol and Multisubstance Use in the Veterans Aging Cohort StudyU01AA020790 · NIAAA · YALE UNIVERSITY · PI JUSTICE, AMY CAROLINE · 2011 to 2020
$7.7M
Mechanisms of human papillomavirus entryR35CA242462 · NCI · YALE UNIVERSITY · PI Daniel C. Dimaio · 2020 to 2026
$6.9M
Sex Disparities in Overall Response to ART Among HIV Infected IndividualsU24AA020794 · NIAAA · YALE UNIVERSITY · PI JUSTICE, AMY CAROLINE · 2011 to 2020
$5.5M
Retrograde TGN/Golgi transport and nuclear targeting of HPV during entryR01AI150897 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Daniel C. Dimaio, Billy Tsai · 2020 to 2026
$3.5M
(PQ1) Lipid Metabolism, Inflammation, and T cell Dysfunction in HIV-associated CancerR01CA206483 · NCI · YALE UNIVERSITY · PI EMU, BRINDA, KAECH, SUSAN M · 2017 to 2021
$3.2M
(PQ4)HIV and Aging Mechanisms for Hepatocellular CancerR01CA206465 · NCI · YALE UNIVERSITY · PI JUSTICE, AMY CAROLINE, LO RE, VINCENT · 2016 to 2020
$2.5M
NCI NIH HHS P30 CA016359NCI NIH HHS P50 CA196530NCI NIH HHS R01 CA206465NCI NIH HHS R01 CA206483NCI NIH HHS R35 CA242462NIAAA NIH HHS U01 AA020790NIAAA NIH HHS U10 AA013566NIAAA NIH HHS U24 AA020794NIAID NIH HHS R01 AI150897NIH HHS P30CA016359NIH HHS R01 CA206465
6 · The paper itself

Abstract

Microbes play important roles in cancer from direct carcinogenic effects to their use in treatment. Cancers caused by microorganisms account for approximately 15% of cancers, primarily in low- and middle-income countries. Unique features of infectious carcinogens include their transmissibility, mutability, and specific immune interactions, which provide challenges and opportunities for cancer prevention and treatment. For these agents, infection control through exposure reduction, antivirals, antibiotics, and vaccines is cancer control. In addition, developing evidence suggests that microorganisms including the human microbiome can indirectly modulate cancer formation and influence the effectiveness and toxicity of cancer treatments. Finally, microorganisms themselves can be used to prevent or treat cancer. The convergence of these factors signals the emergence of a new field, cancer microbiology. Recognition of cancer microbiology will spur research, stimulate cross-disciplinary training, inform drug development, and improve public health.

Indexed as

MicrobiotaNeoplasmsAnti-Bacterial AgentsCarcinogensDelivery of Health CareHumansAnti-Bacterial AgentsCarcinogens

Identifiers

PMID34850062
PMCPMC9086797
OpenAlexW4200462604

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.