Evidence map›Paper›PMID 34849869›Full record

ReviewGigaScience2021

An overview of the National COVID-19 Chest Imaging Database: data quality and cohort analysis.

Dominic Cushnan, Oscar Bennett, Rosalind Berka, Ottavia Bertolli, Ashwin Chopra, Samie Dorgham, Alberto Favaro, Tara Ganepola, Mark Halling-Brown, Gergely Imreh and 6 more

Erratum issuedAbstract readReview
In one paragraph

Review in GigaScience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. MedImg: An Integrated Database for Public Medical Images.Genomics, proteomics & bioinformatics · 2025
    Article
  3. Review
  4. Article
  5. Article
  6. Observational
  7. Article
  8. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors.

Dominic CushnanAI Lab, NHSX, Skipton House, 80 London Road, London SE1 6LH, UK.ORCID 0000-0001-6168-327X
Oscar BennettFaculty, 54 Welbeck Street, London W1G 9XS, UK.ORCID 0000-0003-4546-1807
Rosalind BerkaFaculty, 54 Welbeck Street, London W1G 9XS, UK.
Ottavia BertolliFaculty, 54 Welbeck Street, London W1G 9XS, UK.ORCID 0000-0001-8578-3216
Ashwin ChopraFaculty, 54 Welbeck Street, London W1G 9XS, UK.
Samie DorghamFaculty, 54 Welbeck Street, London W1G 9XS, UK.
Alberto FavaroFaculty, 54 Welbeck Street, London W1G 9XS, UK.
Tara GanepolaFaculty, 54 Welbeck Street, London W1G 9XS, UK.ORCID 0000-0002-6231-3542
Mark Halling-BrownScientific Computing, Royal Surrey NHS Foundation Trust, Egerton Road, Guildford GU2 7XX, UK.ORCID 0000-0002-6247-4768
Gergely ImrehFaculty, 54 Welbeck Street, London W1G 9XS, UK.ORCID 0000-0001-7892-0366
Joseph JacobUCL Respiratory, 1st Floor, Rayne Institute, University College London, London WC1E 6JF, UK.ORCID 0000-0002-8054-2293
Emily JeffersonHealth Data Research UK, Gibbs Building, 215 Euston Road, London NW1 2BE, UK.ORCID 0000-0003-2992-7582
François LemarchandAI Lab, NHSX, Skipton House, 80 London Road, London SE1 6LH, UK.ORCID 0000-0003-3019-2544
Daniel SchofieldAI Lab, NHSX, Skipton House, 80 London Road, London SE1 6LH, UK.ORCID 0000-0002-9251-8653
Jeremy C WyattEmeritus Professor of Digital Healthcare, University of Southampton, Southampton SO17 1BJ, UK.
NCCID Collaborative

Funding

Medical Research Council MR/S010351/1NIHR
6 · The paper itself

Abstract

backgroundThe National COVID-19 Chest Imaging Database (NCCID) is a centralized database containing mainly chest X-rays and computed tomography scans from patients across the UK. The objective of the initiative is to support a better understanding of the coronavirus SARS-CoV-2 disease (COVID-19) and the development of machine learning technologies that will improve care for patients hospitalized with a severe COVID-19 infection. This article introduces the training dataset, including a snapshot analysis covering the completeness of clinical data, and availability of image data for the various use-cases (diagnosis, prognosis, longitudinal risk). An additional cohort analysis measures how well the NCCID represents the wider COVID-19-affected UK population in terms of geographic, demographic, and temporal coverage.

findingsThe NCCID offers high-quality DICOM images acquired across a variety of imaging machinery; multiple time points including historical images are available for a subset of patients. This volume and variety make the database well suited to development of diagnostic/prognostic models for COVID-associated respiratory conditions. Historical images and clinical data may aid long-term risk stratification, particularly as availability of comorbidity data increases through linkage to other resources. The cohort analysis revealed good alignment to general UK COVID-19 statistics for some categories, e.g., sex, whilst identifying areas for improvements to data collection methods, particularly geographic coverage.

conclusionThe NCCID is a growing resource that provides researchers with a large, high-quality database that can be leveraged both to support the response to the COVID-19 pandemic and as a test bed for building clinically viable medical imaging models.

Indexed as

COVID-19Cohort StudiesData AccuracyHumansPandemicsSARS-CoV-2Tomography, X-Ray ComputedCOVID-19machine learningmedical imagingSARS-CoV2thoracic imaging

Identifiers

PMID34849869
PMCPMC8633457

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.