ArticleThe journals of gerontology. Series A, Biological sciences and medical sciences2022
Animal Protein Intake Is Inversely Associated With Mortality in Older Adults: The InCHIANTI Study.
Article in The journals of gerontology. Series A, Biological sciences and medical sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
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Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.
- Pooled it
- Pooled it
- Protein intake and its interaction with dietary patterns on clinical outcomes among older adults.npj aging · 2026Article
- Incidence of depressive symptoms and their associations with lifestyle and social support networks among community-dwelling older adults: a sex-stratified longitudinal study using the JAGES study.BioPsychoSocial medicine · 2025Article
- Dietary Intake of Animal and Plant Proteins and Risk of Gastrointestinal Cancer Mortality: Results from the Golestan Cohort Study.The Journal of nutrition · 2025Article
- Association of Unhealthy Plant-Based Diet with All-Cause Mortality in Chronic Kidney Disease Without Cardiovascular Diseases: A NHANES-Based Study.Journal of multidisciplinary healthcare · 2025Article
- Dietary amino acids intake and all-cause and cause-specific mortality: results from the Golestan Cohort Study.Nutrition journal · 2024Article
- Association between substituting macronutrients and all-cause mortality: a network meta-analysis of prospective observational studies.EClinicalMedicine · 2024Article
- Article
- Article
- Barriers to and Facilitators of the Consumption of Animal-Based Protein-Rich Foods in Older Adults: Re-Analysis with a Focus on Sustainability.Nutrients · 2023Article
- The association of dietary protein intake in three meals and cognitive performance among people over sixty years old.Journal of Alzheimer's disease reportsArticle
Corrections and comments
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Authors and funding
9 authors at 6 institutions in 3 countries.
Funding
Abstract
backgroundIn general, plant protein intake was inversely associated with mortality in studies in middle-aged adults. Our aim was to evaluate the long-term associations of animal and plant protein intake with mortality in older adults.
methodsA prospective cohort study including 1 139 community-dwelling older adults (mean age 75 years, 56% women) living in Tuscany, Italy, followed for 20 years (InCHIANTI study) was analyzed. Dietary intake by food frequency questionnaires and clinical information were assessed 5 times during the follow-up. Protein intakes were expressed as percentages of total energy. Time-dependent Cox regression models adjusted for confounders were used to assess the association between plant and animal protein intake, and mortality.
resultsDuring the 20 years of follow-up (mean: 12 years), 811 deaths occurred (292 of cardiovascular- and 151 of cancer-related causes). Animal protein intake was inversely associated with all-cause (hazard ratio [HR] per 1% of total energy from protein increase, 95% confidence interval [CI]: 0.96, 0.93-0.99) and cardiovascular mortality (HR per 1% of total energy from protein increase, 95% CI: 0.93, 0.87-0.98). Plant protein intake showed no association with any of the mortality outcomes, but an interaction with baseline hypertension was found for all-cause and cardiovascular mortality (p < .05).
conclusionsAnimal protein was inversely associated with all-cause and cardiovascular mortality in older adults. Further studies are needed to provide recommendations on dietary protein intake for older adults.
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