Evidence map›Paper›PMID 34849474›Full record

ArticleiScience2021

An avian embryo patient-derived xenograft model for preclinical studies of human breast cancers.

Loraine Jarrosson, Clélia Costechareyre, Fanny Gallix, Séverine Ciré, Fabien Gay, Olivier Imbaud, Romain Teinturier, Elisabetta Marangoni, Karine Aguéra, Céline Delloye-Bourgeois and 1 more

Open access · goldAbstract read
In one paragraph

Article in iScience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Beyond Rodents: Alternative Animal Models in Colorectal Cancer Research.International journal of molecular sciences · 2025
    Review
  3. Article
  4. Article
  5. Article
  6. Development of aniScience · 2023
    Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Loraine JarrossonOncofactory SAS, 8 Avenue Rockefeller, 69008 Lyon, France.
Clélia CostechareyreOncofactory SAS, 8 Avenue Rockefeller, 69008 Lyon, France.
Fanny GallixErytech Pharma, Research and Development Department, 60 Avenue Rockefeller, 69008 Lyon, France.
Séverine CiréErytech Pharma, Research and Development Department, 60 Avenue Rockefeller, 69008 Lyon, France.
Fabien GayErytech Pharma, Research and Development Department, 60 Avenue Rockefeller, 69008 Lyon, France.
Olivier ImbaudInstitut NeuroMyoGène, University of Lyon, University of Lyon 1 Claude Bernard Lyon 1, NeuroMyoGene Institute, CNRS UMR5310, INSERM U1217, 69007 Lyon, France.
Romain TeinturierOncofactory SAS, 8 Avenue Rockefeller, 69008 Lyon, France.
Elisabetta MarangoniTranslational Research Department, Institut Curie, 26 Rue d'Ulm, 75005 Paris, France.
Karine AguéraErytech Pharma, Research and Development Department, 60 Avenue Rockefeller, 69008 Lyon, France.
Céline Delloye-BourgeoisOncofactory SAS, 8 Avenue Rockefeller, 69008 Lyon, France.
Valérie CastellaniOncofactory SAS, 8 Avenue Rockefeller, 69008 Lyon, France.
Erytech Pharma (France) · FRCentre National de la Recherche Scientifique · FRInstitut Curie · FRInstitut NeuroMyoGène · FRUniversité Claude Bernard Lyon 1 · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lack of preclinical patient-derived xenograft cancer models in which to conduct large-scale molecular studies seriously impairs the development of effective personalized therapies. We report here an

Indexed as

Biological sciences research methodologiesCancerModel organism

Identifiers

PMID34849474
PMCPMC8608609
OpenAlexW3213628942

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.