ArticleiScience2021
Spiny mice activate unique transcriptional programs after severe kidney injury regenerating organ function without fibrosis.
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Article in iScience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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0cells of the map it votes in
38citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
38 citing papers in PubMed, 46 citations in OpenAlex.
- Article
- Lessons from the Axolotl: De Novo Nephron Formation after Nephrectomy.Journal of the American Society of Nephrology : JASN · 2026Article
- Synchronization of the 12-h circatidal rhythm maintains the kidney through repeated cycles of warm reperfusion in the hibernating ground squirrel.Function (Oxford, England) · 2026Article
- What we can learn from hibernators and other adapted animals about organ transplantation: mechanisms of cold resistance and enhanced regeneration.Protein & cell · 2026Article
- Article
- Review
- Resistance to tumorigenesis in the african spiny mouse (Acomys) correlates with upregulation of multiple tumor suppressor genes.Scientific reports · 2026Article
- Applied Anatomical and Morphological Characterization of the Ocular Surface of the African Spiny Mice: Acomys cahirinus.Investigative ophthalmology & visual science · 2026Article
- Thinking outside the mouse: emerging vertebrate models in biomedicine.Biology open · 2026Article
- Article
- Unlocking longevity through the comparative biology of aging.Nature aging · 2025Review
- Acomys cahirinus develop lung stroma distortion but not fibrosis after bleomycin-induced injury.Inflammation and regeneration · 2025Article
- ECM-Focused Proteomic Analysis of Ear Punch Regeneration inJournal of proteome research · 2025Article
- Spiny mice (Acomys) regenerate wounded whisker pad skin with whisker follicles, muscles, and targeted innervation.NPJ Regenerative medicine · 2025Article
- Integrins in the kidney - beyond the matrix.Nature reviews. Nephrology · 2025Review
- Spiny mice (Acomys) have evolved cellular features to support regenerative healing.Annals of the New York Academy of Sciences · 2025Review
- Mathematical modeling reveals cell differentiation processes and progenitor kinetics necessary for proper nephrogenesis.Frontiers in cell and developmental biology · 2025Article
- A comparative transcriptomics analysis of mammalian and non-mammalian acute kidney injury (AKI) models.Frontiers in cell and developmental biology · 2025Article
- Osteoprogenitor cells from non-regenerative bone show greater resistance to cellular stress than those from regenerative bone.Frontiers in cell and developmental biology · 2025Article
- Stroke-induced neuroplasticity in spiny mice in the absence of tissue regeneration.NPJ Regenerative medicine · 2024Article
Corrections and comments
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Authors and funding
19 authors at 2 institutions in 1 country.
Daryl M OkamuraDepartment of Pediatrics, University of Washington, Seattle, WA 98195, USA.
Chris M BrewerDepartment of Laboratory Medicine & Pathology, University of Washington, Seattle, WA 98195, USA.
Paul WakenightCenter for Integrated Brain Research, Seattle Children's Research Institute, Seattle, WA 98105, USA.
Nadia BahramiCenter for Developmental Biology & Regenerative Medicine, Seattle Children's Research Institute, Seattle, WA 98105, USA.
Kristina BernardiCenter for Developmental Biology & Regenerative Medicine, Seattle Children's Research Institute, Seattle, WA 98105, USA.
Amy TranCenter for Developmental Biology & Regenerative Medicine, Seattle Children's Research Institute, Seattle, WA 98105, USA.
Jill OlsonCenter for Developmental Biology & Regenerative Medicine, Seattle Children's Research Institute, Seattle, WA 98105, USA.
Xiaogang ShiCenter for Developmental Biology & Regenerative Medicine, Seattle Children's Research Institute, Seattle, WA 98105, USA.
Szu-Ying YehCenter for Integrated Brain Research, Seattle Children's Research Institute, Seattle, WA 98105, USA.
Adrian PiliponskyCenter for Immunity & Immunotherapies, Seattle Children's Research Institute, Seattle, WA 98105, USA.
Sarah J CollinsCenter for Developmental Biology & Regenerative Medicine, Seattle Children's Research Institute, Seattle, WA 98105, USA.
Elizabeth D NguyenDepartment of Pediatrics, University of Washington, Seattle, WA 98195, USA.
Andrew E TimmsCenter for Developmental Biology & Regenerative Medicine, Seattle Children's Research Institute, Seattle, WA 98105, USA.
James W MacDonaldDepartment of Environmental & Occupational Health, University of Washington, Seattle, WA 98195, USA.
Theo K BammlerDepartment of Environmental & Occupational Health, University of Washington, Seattle, WA 98195, USA.
Branden R NelsonCenter for Integrated Brain Research, Seattle Children's Research Institute, Seattle, WA 98105, USA.
Kathleen J MillenDepartment of Pediatrics, University of Washington, Seattle, WA 98195, USA.
David R BeierDepartment of Pediatrics, University of Washington, Seattle, WA 98195, USA.
Mark W MajeskyDepartment of Pediatrics, University of Washington, Seattle, WA 98195, USA.
Seattle Children's Hospital · USUniversity of Washington · US
Funding
Mechanisms of Brain Dysmorphology in MN1 C-Terminal Truncation Syndrome, a Novel Intellectual Developmental Disability Disorder P50HD103524 · NICHD · UNIVERSITY OF WASHINGTON · PI DANIEL DOHERTY · 2020 to 2026
$9.9MPediatric Nephrology Training ProgramT32DK007662 · NIDDK · UNIVERSITY OF WASHINGTON · PI HINGORANI, SANGEETA · 1991 to 2020
$5.5MAcomys cahrinus: a new paradigm for kidney wound repairR01DK114149 · NIDDK · SEATTLE CHILDREN'S HOSPITAL · PI MAJESKY, MARK W. · 2018 to 2020
$847kNew transgenic tools for mammalian fibrosis and regenerative repair researchR21OD023838 · OD · SEATTLE CHILDREN'S HOSPITAL · PI MILLEN, KATHLEEN JOYCE, NELSON, BRANDEN R · 2017 to 2018
$504kMechanisms of Retinal Ganglion Cell PatterningF32EY015631 · NEI · UNIVERSITY OF WASHINGTON · PI NELSON, BRANDEN R · 2004 to 2007
$142kNEI NIH HHS F32 EY015631NEI NIH HHS L40 EY016882NICHD NIH HHS P50 HD103524NIDDK NIH HHS R01 DK114149NIDDK NIH HHS T32 DK007662NIH HHS R21 OD023838
Abstract
Fibrosis-driven solid organ failure is an enormous burden on global health. Spiny mice (
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Animal physiologyDevelopmental biologyMolecular biology
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.