Evidence map›Paper›PMID 34849131›Full record

ArticlePostepy dermatologii i alergologii2021

Wound coverage by the linen dressing accelerates ulcer healing.

Katarzyna Skórkowska-Telichowska, Justyna Mierziak-Darecka, Magdalena Wrobel-Kwiatkowska, Tomasz Gebarowski, Jan Szopa, Magdalena Zuk

Open access · greenAbstract read
In one paragraph

Article in Postepy dermatologii i alergologii, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Determination of Bioactive Compound Kynurenic Acid inMolecules (Basel, Switzerland) · 2024
    Article
  3. Investigation of the Properties of Linen Fibers and Dressings.International journal of molecular sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Katarzyna Skórkowska-TelichowskaDepartment of Endocrinology and Department of Dermatology, IV Clinical Military Hospital, Wroclaw, Poland.
Justyna Mierziak-DareckaFaculty of Biotechnology, Wroclaw University, Wroclaw, Poland.
Magdalena Wrobel-KwiatkowskaDepartment of Biotechnology and Food Microbiology, Faculty of Biotechnology and Food Sciences, Wroclaw University of Environmental and Life Sciences, Wroclaw, Poland.
Tomasz GebarowskiFaculty of Pharmacy, Department of Basic Medical Sciences, Wroclaw Medical University, Wroclaw, Poland.
Jan SzopaFaculty of Biotechnology, Wroclaw University, Wroclaw, Poland.
Magdalena ZukFaculty of Biotechnology, Wroclaw University, Wroclaw, Poland.
University of Wrocław · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionChronic ulcers are the main cause of morbidity and mortality, and the incidence of chronic wounds is expected to increase given that people live longer and that there are civil diseases.

aimMuch attention in the treatment of wounds concerns a dressing that involves wound cleansing, bacterial balance, exudate management and local tissue in a wound environment. These important elements of the evaluation led to the development of an interactive dressing based entirely on flax raw materials. MATERIAL AND

methodsThe complete dressing for wound coverage was prepared from plant (flax) row products: seedcakes, oil, fiber. The content of bioactive compounds (qualitatively and quantitatively) was tested using chromatographic techniques, and their biological activity during tests on fibroblast cell cultures (NHDF). As a final step the clinical trial were performed.

resultsThe dressings, which help control the microenvironment, combining with exudate using hydrophilic fibre, controlling the flow of exudate from the wound to the dressing were generated. They stimulate the activity in the healing cascade and accelerate the healing process by combining lignocellulose fibre with higher amounts of phenolic compounds, sterols, cannabidiol and unsaturated fatty acids simultaneously with the 3-hydroxybutyrate polymer. All constituents of linen dressing are natural, originate from two types of the engineered flax plant. Pre-clinical data reveal a reasonable reduction in wound size in patients with chronic leg ulcers treated with a linen dressing.

conclusionsFor the first time, a successful application of the innovative interactive linen dressing in the treatment of chronic wounds was noted.

Indexed as

chronic woundspolyhydroxybutyrateskin ulcerationwound dressing

Identifiers

PMID34849131
PMCPMC8610069
OpenAlexW3213137438

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.