Evidence map›Paper›PMID 34849124›Full record

ArticlePostepy dermatologii i alergologii2021

Evaluation of the relationship of

Hatice Uce Ozkol, Gokhan Gorgisen, Can Ates, Halil Özkol, Yasin Tülüce, Hulya Savas, İsmail Musab Gulacar

Open access · goldAbstract read
In one paragraph

Article in Postepy dermatologii i alergologii, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Hatice Uce OzkolDepartment of Dermatology, Faculty of Medicine, Yuzuncu Yil University, Van, Turkey.
Gokhan GorgisenDepartment of Medical Biology, Faculty of Medicine, Yuzuncu Yil University, Van, Turkey.
Can AtesDepartment of Biostatistics, Faculty of Medicine, Yuzuncu Yil University, Van, Turkey.
Halil ÖzkolDepartment of Medical Biology, Faculty of Medicine, Yuzuncu Yil University, Van, Turkey.
Yasin TülüceDepartment of Medical Biology, Faculty of Medicine, Yuzuncu Yil University, Van, Turkey.
Hulya SavasDepartment of Dermatology, Erzincan State Hospital, Erzincan, Turkey.
İsmail Musab GulacarDepartment of Medical Biology, Faculty of Medicine, Yuzuncu Yil University, Van, Turkey.
Van Yüzüncü Yıl Üniversitesi · TRErzincan University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIL-17A and IL-17F cytokines have important roles in the pathogenesis of psoriasis.

aimTo examine the associations of IL-17A rs2275913 and IL-17F rs763780 variants with the development of psoriasis and whether these polymorphisms affect the responsiveness of biological agents. MATERIAL AND

methodsIn our case-controlled study, which included 83 psoriatic patients who were treated with different biological agents and 69 healthy controls, we genotyped IL-17A rs2275913 and IL-17F rs763780 variants using TaqMan probes.

resultsWe did not observe statistically significant changes in genotype frequencies of IL-17A rs2275913 (

conclusionsAccording to our results, we may suggest that rs2275913 variant seems to be associated with disease duration, use of single conventional treatment and responsiveness of PASI90 and PASI100 however both variants have no effect on the susceptibility to psoriasis in the population of Eastern Turkey.

Indexed as

adalimumabIL-17AIL-17Fpsoriasissecukinumabustekinumab

Identifiers

PMID34849124
PMCPMC8610063
OpenAlexW3037600927

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.