Evidence map›Paper›PMID 34849094›Full record

ArticleActa ortopedica brasileira

THE USE OF ANTIFIBRINOLYTICS IN HIP TRAUMA SURGERY IN A PUBLIC HEALTH SYSTEM: A PROSPECTIVE STUDY.

José Alberto Alves Oliveira, Gabriella Cristina Coelho DE Brito, Francisca Magna Prado Bezerra, Carlos Alfredo DE Carvalho, Jonatas Brito DE Alencar, Roberto César Pontes Ibiapina

Open access · goldAbstract read
In one paragraph

Article in Acta ortopedica brasileira. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 66% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. A Survey on Enhanced Recovery After Surgery (ERAS) Elements in Cleft Palate Repair.The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

José Alberto Alves OliveiraUniversidade Federal do Ceará, Fortaleza, Ceará, Brazil.ORCID 0000-0002-6424-1490
Gabriella Cristina Coelho DE BritoHospital Infantil Albert Sabin, Fortaleza, Ceará, Brazil.ORCID 0000-0002-9524-7625
Francisca Magna Prado BezerraHospital Geral de Fortaleza, Serviço de Ortopedia/Traumatologia, Fortaleza, Ceará, Brazil.ORCID 0000-0001-8695-7900
Carlos Alfredo DE CarvalhoInstituto Dr. José Frota, Serviço de Anestesiologia, Fortaleza, Ceará, Brazil.ORCID 0000-0003-2382-8532
Jonatas Brito DE AlencarHospital da Restauração Governador Paulo Guerra, Recife, PE, Brazil.ORCID 0000-0003-3318-5067
Roberto César Pontes IbiapinaHospital Geral de Fortaleza, Serviço de Ortopedia/Traumatologia, Fortaleza, Ceará, Brazil.ORCID 0000-0002-8609-2385
Hospital da Restauração · BRHospital Geral de Fortaleza · BRHospital Infantil Albert Sabin · BRUniversidade Federal do Ceará · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the use of tranexamic acid (TXA) and ε-aminocaproic acid (EACA) in reducing blood loss in hip and proximal femur trauma surgery.

methodsProspective study with 49 patients surgically treated in a trauma hospital between Nov/2015 and Feb/2017. The patients were divided in two groups: TXA (n = 24) and EACA (n = 25). The comparison was made according to gender, age at the time of surgery, ASA, fracture and surgery type, estimated blood loss during surgical approach, hemoglobin and hematocrit levels pre and post-operative, and pharmacological cost. The data was processed using SPSS 22.0 with significance level of p < 0,05.

resultsNo significant difference was found in the variables age, gender, ASA and estimated blood loss during surgical approach. No patient needed blood transfusion. When evaluated post-operatively, the hemoglobin and hematocrit values decrease had no significant difference between the antifibrinolytics (p > 0.05). When analyzing total cost for both pharmacological agents, higher cost was observed in EACA than in TXA (US$ 16.09 - US$ 2.73), resulting in a US$ 13.36 addition per patient.

conclusionAntifibrinolytic use was efficient on lowering the total blood loss, without the need of blood transfusion.

Indexed as

Anti-FibrinolyticHip FracturesSurgery

Identifiers

PMID34849094
PMCPMC8601384
OpenAlexW3213706849

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.