ArticleRNA (New York, N.Y.)2022
Ribosome profiling reveals novel regulation of
Abstract read
In one paragraph
Article in RNA (New York, N.Y.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed.
- Article
- The Interactions of Tau, RNA, and Stress Granules in Neurodegenerative Disease: A Comprehensive Review.Cells · 2026Review
- Blocking RAN translation without altering repeat RNAs rescuesScience (New York, N.Y.) · 2026Article
- Aberrant splicing exonizes C9orf72 repeat expansion in ALS/FTD.Nature neuroscience · 2025Article
- Canonical translation factors eIF1A and eIF5B modulate the initiation step of repeat-associated non-AUG translation.Nucleic acids research · 2025Article
- Cryptic intronic transcriptional initiation generates efficient endogenous mRNA templates for C9orf72-associated RAN translation.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- FMRP regulation of aggrecan mRNA translation controls perineuronal net development.Journal of neurochemistry · 2024Article
- dCas13-mediated translational repression for accurate gene silencing in mammalian cells.Nature communications · 2024Article
- Reconstitution of C9orf72 GGGGCC repeat-associated non-AUG translation with purified human translation factors.Scientific reports · 2023Article
- Translation of dipeptide repeat proteins ineLife · 2023Article
- Translation dysregulation in neurodegenerative diseases: a focus on ALS.Molecular neurodegeneration · 2023Review
- Dissecting the roles of EIF4G homologs reveals DAP5 as a modifier of CGG repeat-associated toxicity in a Drosophila model of FXTAS.Neurobiology of disease · 2023Article
- Review
- Eukaryotic translation initiation factor eIF4G2 opens novel paths for protein synthesis in development, apoptosis and cell differentiation.Cell proliferation · 2023Review
- Specific mechanisms of translation initiation in higher eukaryotes: the eIF4G2 story.RNA (New York, N.Y.) · 2023Review
- RNA Dysmetabolism and Repeat-Associated Non-AUG Translation in Frontotemporal Lobar Degeneration/Amyotrophic Lateral Sclerosis due toJMA journal · 2023Review
- DAP5 drives translation of specific mRNA targets with upstream ORFs in human embryonic stem cells.RNA (New York, N.Y.) · 2022Article
- Ribosome inhibition by C9ORF72-ALS/FTD-associated poly-PR and poly-GR proteins revealed by cryo-EM.Nature communications · 2022Article
- Analysis on the interactions between the first introns and other introns in mitochondrial ribosomal protein genes.Frontiers in microbiology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Heleen M van 't Spijker *Program in Molecular Medicine, University of Massachusetts Chan Medical School, Worcester, Massachusetts 01605, USA.ORCID 0000-0001-7032-1393
Emily E Stackpole *Program in Molecular Medicine, University of Massachusetts Chan Medical School, Worcester, Massachusetts 01605, USA.
Sandra Almeida *Department of Neurology, University of Massachusetts Chan Medical School, Worcester, Massachusetts 01605, USA.
Olga KatsaraDepartment of Microbiology, New York University School of Medicine, New York, New York 10016, USA.
Botao LiuProgram in Molecular Medicine, University of Massachusetts Chan Medical School, Worcester, Massachusetts 01605, USA.
Kuang ShenProgram in Molecular Medicine, University of Massachusetts Chan Medical School, Worcester, Massachusetts 01605, USA.
Robert J SchneiderDepartment of Microbiology, New York University School of Medicine, New York, New York 10016, USA.
Fen-Biao GaoDepartment of Neurology, University of Massachusetts Chan Medical School, Worcester, Massachusetts 01605, USA.
Joel D RichterProgram in Molecular Medicine, University of Massachusetts Chan Medical School, Worcester, Massachusetts 01605, USA.
Funding
POLYADENYLATION AND TRANSLATIONAL CONTROLR01GM046779 · NIGMS · WORCESTER FOUNDATION FOR BIOMEDICAL RES · PI RICHTER, JOEL D · 1992 to 2022
$7.7MInvestigating Common Molecular Pathogenic Pathways in Frontotemporal Dementia Patients iPSC-Derived NeuronsR01NS057553 · NINDS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI Fen-Biao Gao · 2008 to 2026
$4.5MInvestigating Pathogenic Mechanisms of Frontotemporal Dementia Caused by Mutations in CHMP2B and TBK1R37NS057553 · NINDS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI GAO, FEN-BIAO · 2018 to 2024
$4.3MUnderstanding Frontotemporal Dementia Using Drosophila and iPSC ModelsR01NS101986 · NINDS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI Fen-Biao Gao · 2017 to 2026
$3.6MDAP5-dependent translational control and breast cancer metastasisR01CA248397 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI SCHNEIDER, ROBERT JAY · 2020 to 2024
$2.5MFMRP Regulation of Gene ExpressionR01GM135087 · NIGMS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI HUBER, KIMBERLY M., RICHTER, JOEL D · 2020 to 2023
$2.4Mthe mTOR translational control pathway in tamoxifen resistant ER+ breast cancerR01CA207893 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI SCHNEIDER, ROBERT JAY · 2017 to 2021
$2.1MUnderstanding Frontotemporal Dementia Using Drosophila and iPSC ModelsRF1NS101986 · NINDS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI GAO, FEN-BIAO · 2022 to 2022
$2.1MInvestigating Translational De-repression as a Mechanism to Increase Progranulin Levels in iPSC-derived Patient NeuronsR21NS112766 · NINDS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI ALMEIDA, SANDRA · 2019 to 2019
$461kCharacterization of TASK-1 Modulation of Dipeptide Repeat Protein-Mediated Toxicity in iPSC-derived C9ORF72 Patient Neurons.R21NS119952 · NINDS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI ALMEIDA, SANDRA · 2020 to 2020
$461kInhibiting Translation of Endogenous G4C2-Containing RNA As a Novel Therapy for C9ORF72-ALSR21NS109847 · NINDS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI GAO, FEN-BIAO, RICHTER, JOEL D · 2018 to 2019
$461kNCI NIH HHS R01 CA207893NCI NIH HHS R01 CA248397NIGMS NIH HHS R01 GM046779NIGMS NIH HHS R01 GM135087NINDS NIH HHS R01 NS057553NINDS NIH HHS R01 NS101986NINDS NIH HHS R21 NS109847NINDS NIH HHS R21 NS112766NINDS NIH HHS R21 NS119952NINDS NIH HHS R37 NS057553NINDS NIH HHS RF1 NS101986
Abstract
PubMed holds no abstract for this paper.
Indexed as
Peptide Chain Initiation, TranslationalC9orf72 ProteinDinucleotide RepeatsHEK293 CellsHeLa CellsHumansInduced Pluripotent Stem CellsNeural Stem CellsRibosomesRNA, MessengerC9orf72 ProteinC9orf72 protein, humanRNA, MessengerALSC9ORF72DAP5frontotemporal dementiaribosome profilingribosome stallinguORF translation
Identifiers
What OpenQuestion holds
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LicenceCC BY-NC
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.