Evidence map›Paper›PMID 34848529›Full record

ArticleBMJ open2021

Research priorities for the management of complex fractures: a UK priority setting partnership with the James Lind Alliance.

Christopher Patrick Bretherton, Henry A Claireaux, Jonathan Gower, Shan Martin, Angela Thornhill, Louise Johnson, Lucy Silvester, Rebecca Samantha Kearney, Mark Baxter, Paul Dixon and 3 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07751107 (Early Virtual Ankle Rehabilitation), which is not on this map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07751107 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Early Virtual Ankle Rehabilitation (EVAR): A Proof-of-concept Feasibility Study Exploring Patient Acceptability Using Qualitative Interviews With Nested Quantitative Analysis.

TypeinterventionalSponsorUniversity of NottinghamRan2026 to 2027Enrolled30ConditionsAnkle FractureArmsEVAR, EMADE
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. European Glaucoma Society research priorities for glaucoma care.The British journal of ophthalmology · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 10 institutions in 4 countries.

Christopher Patrick BrethertonNuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK christopher.bretherton@ndorms.ox.ac.uk.ORCID 0000-0001-9569-0734
Henry A ClaireauxNuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.
Jonathan GowerJames Lind Alliance, Southampton, UK.
Shan MartinPatient Representative, Wessex, UK.
Angela ThornhillPatient Representative, East Midlands, UK.
Louise JohnsonClinical Psychology, Leeds General Infirmary, Leeds, UK.
Lucy SilvesterPhysiotherapy, University Hospitals Coventry and Warwickshire NHS Trust, Coventry, UK.
Rebecca Samantha KearneyWarwick Clinical Trials Unit, University of Warwick, Coventry, UK.ORCID 0000-0002-8010-164X
Mark BaxterOrthogeriatrics, University Hospital Southampton NHS Foundation Trust, Southampton, UK.
Paul DixonTrauma & Orthopaedic Surgery, James Cook University Hospital, Middlesbrough, UK.
Victoria GiblinPlastic Surgery, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.
Xavier Luke GriffinTrauma & Orthopaedic Surgery, Queen Mary University of London, London, UK.ORCID 0000-0003-2976-7523
William EardleyTrauma & Orthopaedic Surgery, James Cook University Hospital, Middlesbrough, UK.
James Cook University Hospital · GBNuffield Orthopaedic Centre · GBJames Lind Institute · CHLeeds General Infirmary · GBNIHR Research Delivery Network · GBQueen Mary University of London · GBTexas Plastic Surgery · USUniversity Hospitals Coventry and Warwickshire NHS Trust · GBUniversity Hospital Southampton NHS Foundation Trust · GBUniversity of Warwick · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine research priorities for the management of complex fractures, which represent the shared priorities of patients, their families, carers and healthcare professionals. DESIGN/

settingA national (UK) research priority setting partnership.

participantsPeople who have experienced a complex fracture, their carers and relatives, and relevant healthcare professionals and clinical academics involved in treating patients with complex fractures. The scope includes open fractures, fractures to joints broken into multiple pieces, multiple concomitant fractures and fractures involving the pelvis and acetabulum.

methodsA multiphase priority setting exercise was conducted in partnership with the James Lind Alliance over 21 months (October 2019 to June 2021). A national survey asked respondents to submit their research uncertainties which were then combined into several indicative questions. The existing evidence was searched to ensure that the questions had not already been sufficiently answered. A second national survey asked respondents to prioritise the research questions. A final shortlist of 18 questions was taken to a stakeholder workshop, where a consensus was reached on the top 10 priorities.

resultsA total of 532 uncertainties, submitted by 158 respondents (including 33 patients/carers) were received during the initial survey. These were refined into 58 unique indicative questions, of which all 58 were judged to be true uncertainties after review of the existing evidence. 136 people (including 56 patients/carers) responded to the interim prioritisation survey and 18 questions were taken to a final consensus workshop between patients, carers and healthcare professionals. At the final workshop, a consensus was reached for the ranking of the top 10 questions.

conclusionsThe top 10 research priorities for complex fracture include questions regarding rehabilitation, complications, psychological support and return to life-roles. These shared priorities will now be used to guide funders and teams wishing to research complex fractures over the coming decade.

Indexed as

Biomedical ResearchFractures, BoneCaregiversHealth PersonnelHealth PrioritiesHumansUnited Kingdomcomplex fracturespriority settingtrauma

Identifiers

PMID34848529
PMCPMC8634374
OpenAlexW3215221222

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.