Evidence map›Paper›PMID 34848499›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2022

DSCAM Deficiency Leads to Premature Spine Maturation and Autism-like Behaviors.

Peng Chen, Ziyang Liu, Qian Zhang, Dong Lin, Lu Song, Jianghong Liu, Hui-Feng Jiao, Xinsheng Lai, Suqi Zou, Shunqi Wang and 5 more

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 45 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Role of CPEBs in Learning and Memory.Journal of neurochemistry · 2025
    Review
  10. Article
  11. Article
  12. Review
  13. FromFrontiers in immunology · 2025
    Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Peng ChenSchool of Life Sciences, Nanchang University, Nanchang, 330031, China.
Ziyang LiuSchool of Life Sciences, Nanchang University, Nanchang, 330031, China.
Qian ZhangSchool of Basic Medical Sciences, Nanchang University, Nanchang, 330031, China.
Dong LinSchool of Life Sciences, Nanchang University, Nanchang, 330031, China.
Lu SongState Key Laboratory of Brain and Cognitive Science, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China.
Jianghong LiuState Key Laboratory of Brain and Cognitive Science, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China.
Hui-Feng JiaoSchool of Basic Medical Sciences, Nanchang University, Nanchang, 330031, China.
Xinsheng LaiSchool of Life Sciences, Nanchang University, Nanchang, 330031, China.
Suqi ZouSchool of Life Sciences, Nanchang University, Nanchang, 330031, China.
Shunqi WangSchool of Life Sciences, Nanchang University, Nanchang, 330031, China.
Tian ZhouSchool of Basic Medical Sciences, Nanchang University, Nanchang, 330031, China.
Bao-Ming LiSchool of Life Sciences, Nanchang University, Nanchang, 330031, China.
Li ZhuState Key Laboratory of Brain and Cognitive Science, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China fek@ncu.edu.cn panbingxing@ncu.edu.cn zhuli@ibp.ac.cn.
Bing-Xing PanSchool of Life Sciences, Nanchang University, Nanchang, 330031, China fek@ncu.edu.cn panbingxing@ncu.edu.cn zhuli@ibp.ac.cn.
Erkang FeiSchool of Life Sciences, Nanchang University, Nanchang, 330031, China fek@ncu.edu.cn panbingxing@ncu.edu.cn zhuli@ibp.ac.cn.ORCID 0000-0002-3581-9521
Nanchang University · CNChinese Academy of Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mutations in some cell adhesion molecules (CAMs) cause abnormal synapse formation and maturation, and serve as one of the potential mechanisms of autism spectrum disorders (ASDs). Recently,

Indexed as

AnimalsAutism Spectrum DisorderCell Adhesion MoleculesCells, CulturedChlorocebus aethiopsCOS CellsDendritic SpinesHEK293 CellsHumansMaleMiceMice, Inbred C57BLMice, TransgenicNeurogenesisOrgan Culture TechniquesRatsCell Adhesion MoleculesDscam protein, mouseAutismdendritic spineDSCAMNLGN1

Identifiers

PMID34848499
PMCPMC8805618
OpenAlexW3216534304

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.