Trial reportAmerican journal of infection control2022
Reducing overuse of antibiotics at discharge home: A single-center mixed methods pilot study.
Trial report in American journal of infection control, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 17 citations in OpenAlex.
- Prospective Audit and Feedback by Antibiotic Stewardship Teams to Reduce Antibiotic Overuse at Hospital Discharge: A Stepped-Wedge Cluster-Randomized Clinical Trial.JAMA network open · 2026Trial
- Missed Antibiotic Doses, Microbiology Diagnostic Results, and Antibiotic Prescribing Patterns at Discharge at Two Paediatric Tertiary Hospitals in Zambia: Implications for Antimicrobial Stewardship.Antibiotics (Basel, Switzerland) · 2026Article
- Qualitative assessment of antibiotic stewardship teams' efforts to perform prospective audit-and-feedback at hospital discharge.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2026Article
- An assessment of antimicrobial resistance national action plans and their impact on antibiotic use.BMJ global health · 2025Article
- Influence of Access to Care on Decision-making About Antibiotic Duration at Discharge.Open forum infectious diseases · 2025Article
- Characteristics of Quality Improvement Projects in Health Services: A Systematic Scoping Review.Journal of evidence-based medicine · 2025Article
- Excellence in Antibiotic Stewardship: A Mixed-Methods Study Comparing High-, Medium-, and Low-Performing Hospitals.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024Article
- Length of antibiotic therapy among adults hospitalized with uncomplicated community-acquired pneumonia, 2013-2020.Infection control and hospital epidemiology · 2024Article
- Protocol for a parallel cluster randomized trial of a participatory tailored approach to reduce overuse of antibiotics at hospital discharge: the ROAD home trial.Implementation science : IS · 2024Article
- Pharmacist-led antimicrobial stewardship at transitions of care from inpatient hospital to home: a scoping review.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2024Review
- Impact of an Antimicrobial Stewardship Strategy on Surgical Hospital Discharge: Improving Antibiotic Prescription in the Transition of Care.Antibiotics (Basel, Switzerland) · 2023Article
- Pharmacist gender and physician acceptance of antibiotic stewardship recommendations: An analysis of the reducing overuse of antibiotics at discharge home intervention.Infection control and hospital epidemiology · 2023Article
- WHO Point Prevalence Survey to Describe the Use of Antimicrobials at a Tertiary Care Center in Pakistan: A Situation Analysis for Establishing an Antimicrobial Stewardship Program.Antibiotics (Basel, Switzerland) · 2022Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundAntibiotic overuse at hospital discharge is common and harmful; however, methods to improve prescribing during care transitions have been understudied. We aimed to pilot a pharmacist-facilitated antibiotic timeout prior to discharge.
methodsFrom May 2019 to October 2019, we conducted a single-center, controlled pilot study of a pharmacist-facilitated antibiotic timeout prior to discharge. The timeout addressed key elements of stewardship (eg, duration) and was designed and implemented using iterative cycles with rapid feedback. We evaluated implementation outcomes related to feasibility, including usability, adherence, and acceptability, using mixed methods. Pre versus postintervention antibiotic use at discharge in intervention versus control groups was assessed using logistic regression models controlling for patient characteristics.
resultsPharmacists conducted 288 antibiotic timeouts. Timeouts were feasible (mean 2.5 minutes per timeout) and acceptable (85% [40/48] of hospitalists believed timeouts improved prescribing). Pharmacists recommended an antibiotic change in 25% (73/288) of timeouts with 70% (51/73) of recommended changes accepted by hospitalists. Barriers to adherence included unanticipated and weekend discharges. Compared to control services, there were no differences in antibiotic use after discharge during the intervention.
conclusionsA pharmacist-facilitated antibiotic timeout at discharge was feasible and holds promise as a method to improve antibiotic use at discharge.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.