Evidence map›Paper›PMID 34848117›Full record

ArticleJournal of cardiology2022

Incidence of Atrioventricular Blocks and its Association with In-Hospital Mortality and Morbidity in Patients with Coronavirus Disease 2019.

Nicole Lao, Joseph Lim, Hanad Bashir, Gauranga Mahalwar, Olayinka Adebolu, Caroline Mangira, Jeffrey Courson, Vinayak Hegde

Open access · bronzeAbstract read
In one paragraph

Article in Journal of cardiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Cardiac arrhythmia in COVID-19 patients.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2024
    Review
  5. Effects of COVID-19 on Arrhythmia.Journal of cardiovascular development and disease · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Nicole LaoDepartment of Internal Medicine, Cleveland Clinic Akron General, Akron, OH, USA.
Joseph LimDepartment of Internal Medicine, Cleveland Clinic Akron General, Akron, OH, USA.
Hanad BashirDepartment of Internal Medicine, Cleveland Clinic Akron General, Akron, OH, USA.
Gauranga MahalwarDepartment of Internal Medicine, Cleveland Clinic Akron General, Akron, OH, USA.
Olayinka AdeboluDepartment of Internal Medicine, Cleveland Clinic Akron General, Akron, OH, USA.
Caroline MangiraDepartment of Research, Cleveland Clinic Akron General, Akron, OH, USA.
Jeffrey CoursonDepartment of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, OH, USA.
Vinayak HegdeDepartment of Cardiovascular Medicine, Heart, Vascular and Thoracic Institute, Cleveland Clinic Akron General, Akron, OH, USA. Electronic address: HegdeV@ccf.org.
Cleveland Clinic · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCardiovascular sequelae of coronavirus disease 2019 (COVID-19) infection have been explored by clinicians and researchers all over the world.

objectiveThe purpose of this study was to evaluate the incidence of atrioventricular block (AV) in patients hospitalized for COVID-19 and its association between in-hospital morbidity and mortality.

methodsIn-hospital electrocardiograms (ECGs) of 438 patients were compared with their prior or baseline ECGs to ascertain the development of new onset AV block. Patients who developed new AV blocks were then followed at 30 and 90 days post-discharge to check for resolution of AV block. Demographic characteristics, clinical characteristics, and complications during their hospital stay were evaluated. Major complications including respiratory failure requiring oxygen supplementation and mechanical ventilation, sepsis, deep vein thrombosis, elevated troponins, hospital and intensive care unit (ICU) length of stay, as well as death were compared between those who developed new onset AV blocks and those who did not.

resultsBased on our single center study, the incidence of new onset AV blocks among patients admitted for COVID-19 during the study period was 5.5 cases per 100 patients. New onset AV blocks were not associated with longer hospital and ICU length of stay, increased intubation rates, or increased mortality.

conclusionAlthough the development of a new onset AV block is most likely multifactorial and not solely due to COVID-19, it is still important for clinicians to be mindful about the possibility of developing symptomatic bradycardia and life-threatening arrhythmias in patients admitted for COVID-19. This can be achieved by appropriate rhythm monitoring in-patient but the need for a cardiac event monitor upon discharge is unlikely to be necessary. Careful history taking, including family and drug use history is also of great importance as emerging drug therapies for COVID-19 have potential arrhythmogenic effects.

Indexed as

Atrioventricular BlockCOVID-19AftercareHospital MortalityHumansIncidencePatient DischargeSARS-CoV-2ArrhythmiasAtrioventricular blockCardiologyCOVID-19Pandemic

Identifiers

PMID34848117
PMCPMC8557989
OpenAlexW3210261647

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.