ArticleBMC public health2021
Factors associated with an interruption in treatment of people living with HIV in USAID-supported states in Nigeria: a retrospective study from 2000-2020.
Article in BMC public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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12 citing papers in PubMed.
- Interruption in treatment and its risk factors among adults living with HIV in Uganda: a cross-sectional study.AIDS research and therapy · 2026Article
- Implementation of male-specific motivational interviewing in Malawi: an assessment of intervention fidelity and barriers to scale-up.BMJ global health · 2026Article
- Predictors of HIV treatment interruption among people living with HIV in 6 regions in Ghana: a retrospective cohort study.BMC public health · 2026Article
- Determinants of return to HIV treatment after interruption on ART among HIV positive clients in Katakwi District, Uganda.PloS one · 2026Article
- Return to care of children and adolescents living with HIV who missed their clinic visits or were lost to follow-up: a continuous quality improvement study in Uganda.BMJ open quality · 2025Article
- Retention of HIV clients in care: A comparative study to highlight the benefit of HIV clinical mentorship program in Nasarawa State, Nigeria.Journal of public health research · 2025Article
- Antiretroviral treatment outcomes and survival pattern of people living with HIV in Bauchi State, Nigeria.PloS one · 2025Article
- Article
- A retrospective study of tuberculosis prevalence and associated factors among HIV-positive key populations in Nigeria.PLOS global public health · 2024Article
- Identifying efficient linkage strategies for men (IDEaL): a study protocol for an individually randomised control trial.BMJ open · 2023Article
- Predictors of the observed high prevalence of loss to follow-up in ART-experienced adult PLHIV: a retrospective longitudinal cohort study in the Tanga Region, Tanzania.BMC infectious diseases · 2023Article
- Antiretroviral treatment interruption and resumption within 16 weeks among HIV-positive adults in Jinan, China: a retrospective cohort study.Frontiers in public health · 2023Article
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Abstract
backgroundPatient interruption of antiretroviral therapy (ART) continues to limit HIV programs' progress toward epidemic control. Multiple factors have been associated with client interruption in treatment (IIT)- including age, gender, CD4 count, and education level. In this paper, we explore the factors associated with IIT in people living with HIV (PLHIV) in United States Agency for International Development (USAID)-supported facilities under the U.S. President's Emergency Plan for AIDS Relief (PEPFAR) program in Nigeria.
methodsWe conducted cross-sectional analyses on data obtained from Nigeria's National Data Repository (NDR), representing a summarized record of 573 630 ART clients that received care at 484 PEPFAR/USAID-supported facilities in 16 states from 2000-2020. IIT was defined as no clinical contact for 28 days or more after the last expected clinical contact. Univariate and multivariate logistic regression models were computed to explore the factors associated with IIT. The variables included in the analysis were sex, age group, zone, facility level, regimen line, multi-month dispensing (MMD), and viral load category.
resultsOf the 573 630 clients analysed in this study, 32% have been recorded as having interrupted treatment. Of the clients investigated, 66% were female (32% had interrupted treatment), 39% were aged 25-34 at their last ART pick-up date (with 32% of them interrupted treatment), 59% received care at secondary level facilities (37% interrupted treatment) and 38% were last receiving between three- to five-month MMD (with 10% of these interrupted treatment). Those less likely to interrupt ART were males (aOR = 0.91), clients on six-month MMD (aOR = 0.01), adults on 2
conclusionsSex, zone, facility level, regimen line, MMD, and VL were significantly associated with IIT. MMD of three months and longer (especially six months) had better retention on ART than those on shorter MMD. Not having a VL on record was associated with a considerable risk of IIT.
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