Evidence map›Paper›PMID 34847775›Full record

ArticleOpen biology2021

MYC regulates metabolism through vesicular transfer of glycolytic kinases.

Alexia Tsakaneli, Victor Corasolla Carregari, Martina Morini, Alessandra Eva, Giuliana Cangemi, Olesya Chayka, Evgeny Makarov, Sandra Bibbò, Emily Capone, Gianluca Sala and 7 more

Open access · goldAbstract readComparative Study
In one paragraph

Article in Open biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 7 institutions in 4 countries.

Alexia TsakaneliInstitute of Environment, Health and Societies, Department of Life Sciences, Brunel University London, UB8 3PH Uxbridge, UK.
Victor Corasolla CarregariGlycoProteomics Laboratory, Department of Parasitology, Institute of Biomedical Sciences, University of Sao Paulo, Av. Prof. Lineu Prestes, 1374 Sao Paulo, Brazil.
Martina MoriniLaboratorio di Biologia Molecolare, IRCCS Istituto G. Gaslini, Genoa, Italy.
Alessandra EvaLaboratorio di Biologia Molecolare, IRCCS Istituto G. Gaslini, Genoa, Italy.
Giuliana CangemiLaboratorio di Analisi, IRCCS Istituto G. Gaslini, Genoa, Italy.
Olesya ChaykaInstitute of Environment, Health and Societies, Department of Life Sciences, Brunel University London, UB8 3PH Uxbridge, UK.
Evgeny MakarovInstitute of Environment, Health and Societies, Department of Life Sciences, Brunel University London, UB8 3PH Uxbridge, UK.
Sandra BibbòDepartment of Innovative Technologies in Medicine and Dentistry, University of Chieti-Pescara, Center for Advanced Studies and Technology (CAST) Chieti, Italy.
Emily CaponeDepartment of Innovative Technologies in Medicine and Dentistry, University of Chieti-Pescara, Center for Advanced Studies and Technology (CAST) Chieti, Italy.
Gianluca SalaDepartment of Innovative Technologies in Medicine and Dentistry, University of Chieti-Pescara, Center for Advanced Studies and Technology (CAST) Chieti, Italy.
Vincenzo De LaurenziDepartment of Innovative Technologies in Medicine and Dentistry, University of Chieti-Pescara, Center for Advanced Studies and Technology (CAST) Chieti, Italy.
Evon PoonDivision of Clinical Studies and Cancer Therapeutics, The Institute of Cancer Research, London, UK.
Louis CheslerDivision of Clinical Studies and Cancer Therapeutics, The Institute of Cancer Research, London, UK.
Luisa PieroniDepartment of Experimental Neuroscience, Proteomics and Metabonomics Unit, Fondazione Santa Lucia-IRCCS, Rome, Italy.
Martin R LarsenDepartment of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark.
Giuseppe PalmisanoGlycoProteomics Laboratory, Department of Parasitology, Institute of Biomedical Sciences, University of Sao Paulo, Av. Prof. Lineu Prestes, 1374 Sao Paulo, Brazil.
Arturo SalaInstitute of Environment, Health and Societies, Department of Life Sciences, Brunel University London, UB8 3PH Uxbridge, UK.ORCID 0000-0002-2841-7866
Brunel University of London · GBUniversity of Chieti-Pescara · ITIstituto Giannina Gaslini · ITInstitute of Cancer Research · GBUniversidade de São Paulo · BRFondazione Santa Lucia · ITUniversity of Southern Denmark · DK

Funding

Cancer Research UK 18339Cancer Research UK 28278
6 · The paper itself

Abstract

Amplification of the proto-oncogene

Indexed as

Carrier ProteinsCell Line, TumorCell ProliferationChildExtracellular VesiclesGene AmplificationGene Expression Regulation, NeoplasticGene Regulatory NetworksGlycolysisHexokinaseHumansMass SpectrometryMembrane ProteinsNeuroblastomaN-Myc Proto-Oncogene ProteinPhosphorylationCarrier ProteinsHexokinaseHK2 protein, humanMembrane ProteinsMYCN protein, humanN-Myc Proto-Oncogene ProteinThyroid Hormone-Binding ProteinsThyroid Hormonesextracellular vesiclesMYCMYCNneuroblastomaWarburg effect

Identifiers

PMID34847775
PMCPMC8633805
OpenAlexW3215295401

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.