Evidence map›Paper›PMID 34847772›Full record

ArticleOpen biology2021

Structure and

Nehad Noby, Husam Sabah Auhim, Samuel Winter, Harley L Worthy, Amira M Embaby, Hesham Saeed, Ahmed Hussein, Christopher R Pudney, Pierre J Rizkallah, Stephen A Wells and 1 more

Open access · goldAbstract read
In one paragraph

Article in Open biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 3 countries.

Nehad NobyDepartment of Biotechnology, Institute of Graduate Studies and Research, Alexandria University, Alexandria, Egypt.ORCID 0000-0002-3420-6168
Husam Sabah AuhimSchool of Biosciences, Molecular Biosciences Division, Cardiff University, Cardiff CF10 3AX, UK.ORCID 0000-0003-1086-741X
Samuel WinterDepartment of Biology and Biochemistry, University of Bath, Bath BA2 7AY, UK.
Harley L WorthySchool of Biosciences, Molecular Biosciences Division, Cardiff University, Cardiff CF10 3AX, UK.
Amira M EmbabyDepartment of Biotechnology, Institute of Graduate Studies and Research, Alexandria University, Alexandria, Egypt.ORCID 0000-0001-8068-4200
Hesham SaeedDepartment of Biotechnology, Institute of Graduate Studies and Research, Alexandria University, Alexandria, Egypt.
Ahmed HusseinDepartment of Biotechnology, Institute of Graduate Studies and Research, Alexandria University, Alexandria, Egypt.
Christopher R PudneyDepartment of Biology and Biochemistry, University of Bath, Bath BA2 7AY, UK.
Pierre J RizkallahSchool of Medicine, Cardiff University, Cardiff CF14 4XN, UK.ORCID 0000-0002-9290-0369
Stephen A WellsDepartment of Physics, University of Bath, Bath BA2 7AY.
D Dafydd JonesSchool of Biosciences, Molecular Biosciences Division, Cardiff University, Cardiff CF10 3AX, UK.ORCID 0000-0001-7709-3995
Cardiff University · GBAlexandria University · EGUniversity of Bath · GBUniversity of Baghdad · IQ

Funding

Biotechnology and Biological Sciences Research Council BB/M000249/1
6 · The paper itself

Abstract

Here we determined the structure of a cold active family IV esterase (EstN7) cloned

Indexed as

BacillusBacterial ProteinsCatalytic DomainCold TemperatureCrystallography, X-RayEsterasesHydrophobic and Hydrophilic InteractionsModels, MolecularMolecular Dynamics SimulationProtein ConformationThermodynamicsBacterial ProteinsEsterasesenzyme structuremolecular dynamicsprotein stabilityserine esterasestructure–function

Identifiers

PMID34847772
PMCPMC8633780
OpenAlexW3216685688

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.