Evidence map›Paper›PMID 34847569›Full record

ArticleFunction (Oxford, England)2021

B

Bruce R Stevens, J Clive Ellory, Robert L Preston

Open access · goldAbstract readComment
In one paragraph

Article in Function (Oxford, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Association of specificFrontiers in immunology · 2024
    Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Long COVID: Is there a kidney link?Frontiers in medicine · 2023
    Article
  14. Article
  15. ACE2, BCurrent opinion in structural biology · 2022
    Review
  16. The collectrin-like part of the SARS-CoV-1 and -2 receptor ACE2 is shed by the metalloproteinases ADAM10 and ADAM17.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2022
    Article
  17. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Bruce R StevensDepartment of Physiology and Functional Genomics, University of Florida College of Medicine, Gainesville, FL, 32610, USA.ORCID 0000-0003-2109-8724
J Clive ElloryDepartment of Physiology, Anatomy and Genetics, University of Oxford, Oxford, OX1 3PT, UK.
Robert L PrestonSchool of Biological Sciences, Illinois State University, Normal, IL, 61790, USA.
Illinois State University · USUniversity of Florida · USUniversity of Oxford · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The SARS-CoV-2 receptor, angiotensin-converting enzyme-2 (ACE2), is expressed at levels of greatest magnitude in the small intestine as compared with all other human tissues. Enterocyte ACE2 is coexpressed as the apical membrane trafficking partner obligatory for expression and activity of the B

Indexed as

Amino Acids, NeutralAmino Acid Transport Systems, NeutralCOVID-19Amino Acid Transport SystemsAngiotensin-Converting Enzyme 2HumansMolecular Docking SimulationPeptidyl-Dipeptidase ASARS-CoV-2Amino Acids, NeutralAmino Acid Transport SystemsAmino Acid Transport Systems, NeutralAngiotensin-Converting Enzyme 2Peptidyl-Dipeptidase A6M17ACE2B0AT1intestinemembraneneutral amino acid transportradiation inactivationsodium-dependent transporttransporter

Identifiers

PMID34847569
PMCPMC8194517
OpenAlexW3163737529

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.