Evidence map›Paper›PMID 34847412›Full record

ArticleGait & posture2022

Investigating the underlying biomechanical mechanisms leading to falls in long-term ankle-foot orthosis and functional electrical stimulator users with chronic stroke.

Masood Nevisipour, Claire F Honeycutt

Open access · greenAbstract read
In one paragraph

Article in Gait & posture, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. The Role of Functional Electrical Stimulation in Stroke Rehabilitation: A Preliminary Study.Physiotherapy research international : the journal for researchers and clinicians in physical therapy · 2025
    Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Masood NevisipourSchool for Engineering of Matter, Transport & Energy, Arizona State University, Tempe, AZ, USA. Electronic address: mnevisip@asu.edu.
Claire F HoneycuttSchool of Biological and Health System Engineering, Arizona State University, Tempe, AZ, USA. Electronic address: cfhoneyc@asu.edu.
Arizona State University · US

Funding

Mechanisms underlying impaired postural corrections following strokeR00HD073240 · NICHD · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI HONEYCUTT, CLAIRE F. · 2015 to 2017
$683k
NICHD NIH HHS R00 HD073240
6 · The paper itself

Abstract

backgroundAnkle-foot-orthoses (AFOs) and functional electrical stimulators (FES) are commonly prescribed to treat foot-drop in individuals with stroke. Despite well-established positive impacts of AFO and FES devices on balance and gait, AFO and FES-users still fall at a high rate.

objectiveThe objective of this study was to investigate 1) the underlying biomechanical mechanisms leading to a fall in long-term AFO and FES-users with chronic stroke and 2) the impacts of AFOs and FES devices on fall outcomes and compensatory stepping response of long-term users with chronic stroke.

methodsFall outcomes as well as kinematics and kinetics of compensatory stepping response of 42 individuals with chronic stroke (14 AFO-users, 10 FES-users, 18 Non-users) were evaluated during trip-like treadmill perturbations. AFO and FES-users were evaluated with and without their device.

resultsChronic AFO and FES-users fell 2.50 and 2.77 times more than Non-users. The most robust differences between AFO/FES-users and Non-users were 1) Reduced capacity to stabilize the trunk through reduction in forward whole-body angular momentum and 2) diminished capability to prepare and generate a second step using the paretic leg. Provocatively, the removal of AFO and FES devices did not decease/increase falls or change kinematics. SIGNIFICANCE: It is well-established that AFOs/FES devices have a positive impact on static balance and decrease community falls by increasing toe clearance thus preventing trips/stumbles. However, our results suggest that once a trip occurs, these devices do not adequately assist recovery of balance. Specifically, current AFO and FES devices do not assist with second step generation or trunk control. Future studies should explore new devices or training paradigms that target enhancing trunk control and paretic compensatory stepping to decrease falls in this population.

Indexed as

Electric Stimulation TherapyFoot OrthosesGait Disorders, NeurologicStrokeStroke RehabilitationAnkleBiomechanical PhenomenaGaitHumansAnkle foot orthosisFall biomechanicsFunctional electrical stimulationReactive stepping responseStroke rehabilitation

Identifiers

PMID34847412
PMCPMC8900662
OpenAlexW3217039277

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.