Evidence map›Paper›PMID 34847355›Full record

ReviewNeuron2022

A matter of space and time: Emerging roles of disease-associated proteins in neural development.

Georgia Panagiotakos, Sergiu P Pasca

Open access · greenAbstract readReview
In one paragraph

Review in Neuron, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Genetics of human brain development.Nature reviews. Genetics · 2024
    Review
  9. Review
  10. Pleiotropy of autism-associated chromatin regulators.Development (Cambridge, England) · 2023
    Article
  11. Article
  12. Review
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Georgia PanagiotakosDepartment of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA, USA; Kavli Institute for Fundamental Neuroscience, University of California, San Francisco, San Francisco, CA, USA; Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, San Francisco, CA, USA. Electronic address: georgia.panagiotakos@ucsf.edu.
Sergiu P PascaDepartment of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA; Stanford Brain Organogenesis, Wu Tsai Neurosciences Institute, Stanford University, Stanford, CA, USA. Electronic address: spasca@stanford.edu.
Neurosciences Institute · USUniversity of California, San Francisco · US

Funding

Role of L-type Calcium Channels in Human Interneuron Migration and IntegrationR01MH115012 · NIMH · STANFORD UNIVERSITY · PI PASCA, SERGIU · 2018 to 2022
$2.8M
Calcium-Dependent Regulation of Neural Fate in Development and DiseaseR01MH125004 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI PANAGIOTAKOS, GEORGIA · 2021 to 2025
$2.0M
Cell type signaling specificity of the neurodevelopmental disease-associated DYRK1A kinaseR56MH127075 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI PANAGIOTAKOS, GEORGIA · 2021 to 2021
$378k
NIMH NIH HHS R01 MH115012NIMH NIH HHS R01 MH125004NIMH NIH HHS R56 MH127075
6 · The paper itself

Abstract

Recent genetic studies of neurodevelopmental disorders point to synaptic proteins and ion channels as key contributors to disease pathogenesis. Although many of these proteins, such as the L-type calcium channel Ca

Indexed as

Calcium Channels, L-TypeNeurogenesisFemaleHumansNeuronsPregnancyProtein IsoformsCalcium Channels, L-TypeProtein Isoforms

Identifiers

PMID34847355
PMCPMC8776599
OpenAlexW3217809045

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.