Evidence map›Paper›PMID 34847259›Full record

ArticleCancer2022

Perceived financial decline related to breast reconstruction following mastectomy in a diverse population-based cohort.

Nicholas L Berlin, Paul Abrahamse, Adeyiza O Momoh, Steven J Katz, Reshma Jagsi, Ann S Hamilton, Kevin C Ward, Sarah T Hawley

Open access · bronzeAbstract read
In one paragraph

Article in Cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
2.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 12 citations in OpenAlex.

  1. Prognostic factors for return to work in breast cancer survivors.The Cochrane database of systematic reviews · 2025
    Pooled it
  2. Evaluation of financial toxicity and associated factors in female patients with breast cancer: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Individualized Out-of-Pocket Price Estimators for "Shoppable" Surgical Procedures: A Nationwide Cross-Sectional Study of US Hospitals.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2022
    Article
  10. Financial Toxicity Considerations in Breast Reconstruction: Recommendations for Research and Practice.Women's health issues : official publication of the Jacobs Institute of Women's Health
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Nicholas L BerlinSection of Plastic Surgery, University of Michigan, Ann Arbor, Michigan.ORCID 0000-0002-1026-7011
Paul AbrahamseDepartment of Internal Medicine, University of Michigan, Ann Arbor, Michigan.
Adeyiza O MomohSection of Plastic Surgery, University of Michigan, Ann Arbor, Michigan.
Steven J KatzDepartment of Internal Medicine, University of Michigan, Ann Arbor, Michigan.
Reshma JagsiDepartment of Radiation Oncology, University of Michigan, Ann Arbor, Michigan.ORCID 0000-0001-6562-1228
Ann S HamiltonDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California.
Kevin C WardDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia.
Sarah T HawleyDepartment of Internal Medicine, University of Michigan, Ann Arbor, Michigan.
University of Michigan · USEmory University · USUniversity of Southern California · US

Funding

The Challenge of Individualizing Treatments for Patients with Breast CancerP01CA163233 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HOFER, TIMOTHY P. · 2012 to 2016
$13.4M
CDC HHS 5NU58DP006344CDC HHS 5NU58DP006352-03-00NCCDPHP CDC HHS NU58DP006344NCI NIH HHS HHSN26100001NCI NIH HHS HHSN261201800003CNCI NIH HHS HHSN261201800003INCI NIH HHS HHSN261201800009CNCI NIH HHS HHSN261201800009INCI NIH HHS HHSN261201800015CNCI NIH HHS HHSN261201800015INCI NIH HHS HHSN261201800032CNCI NIH HHS HHSN261201800032INCI NIH HHS P01 CA163233
6 · The paper itself

Abstract

backgroundDespite mandated insurance coverage for breast reconstruction following mastectomy, health care costs are increasingly passed on to women through cost-sharing arrangements and high-deductible health plans. In this population-based study, the authors assessed perceived financial and employment declines related to breast reconstruction following mastectomy.

methodsWomen with early-stage breast cancer (stages 0-II) diagnosed between July 2013 and May 2015 who underwent mastectomy were identified through the Surveillance, Epidemiology, and End Results registries of Georgia and Los Angeles and were surveyed. Primary outcome measures included patients' appraisal of their financial and employment status after cancer treatment. Multivariable models evaluated the association between breast reconstruction and primary outcomes.

resultsAmong 883 patients with breast cancer who underwent mastectomy, 44.2% did not undergo breast reconstruction, and 55.8% underwent reconstruction. Overall, 21.9% of the cohort reported being worse off financially since their diagnosis (25.8% with reconstruction vs 16.6% without reconstruction; P = .002). Women who underwent reconstruction reported higher out-of-pocket medical expenses (32.1% vs 15.6% with expenses greater than $5000; P < .001). Reconstruction was independently associated with a perceived decline in financial status (odds ratio, 1.92; 95% confidence interval, 1.15-3.22; P = .013). Among women who were employed at the time of their diagnosis, there was no association between reconstruction and a perceived decline in employment status (P = .927).

conclusionsIn this diverse cohort of women who underwent mastectomy, those who elected to undergo reconstruction experienced higher out-of-pocket medical expenses and self-reported financial decline. Patients, providers, and policymakers should be aware of the potential financial implications related to reconstruction despite mandatory insurance coverage.

Indexed as

Breast NeoplasmsMammaplastyCohort StudiesFemaleHumansInsurance CoverageMastectomybreast reconstructionfinancial toxicityout-of-pocket costs

Identifiers

PMID34847259
PMCPMC8882150
OpenAlexW3215371216

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.