Evidence map›Paper›PMID 34847258›Full record

ArticleNeuropathology and applied neurobiology2022

Long-standing multiple system atrophy-Parkinsonism with limbic and FTLD-type α-synuclein pathology.

David G Coughlin, Ian Dryden, Vanessa S Goodwill, Donald P Pizzo, Brenton Wright, Stephanie Lessig, Douglas Galasko, Ian R MacKenzie, Annie Hiniker

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neuropathology and applied neurobiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Comorbid pathologies and their impact on multiple system atrophy: current view.Journal of neural transmission (Vienna, Austria : 1996) · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Multiple system atrophy with hippocampal pathology.Brain pathology (Zurich, Switzerland) · 2022
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

David G CoughlinDepartment of Neurosciences, University of California San Diego, La Jolla, CA, USA.
Ian DrydenDepartment of Pathology, University of California San Diego, La Jolla, CA, USA.
Vanessa S GoodwillDepartment of Pathology, University of California San Diego, La Jolla, CA, USA.ORCID 0000-0001-7665-7146
Donald P PizzoDepartment of Pathology, University of California San Diego, La Jolla, CA, USA.
Brenton WrightDepartment of Neurosciences, University of California San Diego, La Jolla, CA, USA.
Stephanie LessigDepartment of Neurosciences, University of California San Diego, La Jolla, CA, USA.
Douglas GalaskoDepartment of Neurosciences, University of California San Diego, La Jolla, CA, USA.
Ian R MacKenzieDepartment of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Annie HinikerDepartment of Pathology, University of California San Diego, La Jolla, CA, USA.ORCID 0000-0002-0055-6610
University of California San Diego · USUniversity of British Columbia · CA

Funding

UCSD Shiley-Marcos Alzheimer's Disease Research Center P30P30AG062429 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Mark W Bondi · 2019 to 2026
$34.9M
Chemical-Genetic Approaches to Define Lrrk2 Kinase Function in Parkinson DiseaseK08NS090633 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HINIKER, ANNIE E · 2014 to 2018
$1.1M
Pathological and cognitive correlations of real time quaking induced conversion in LBD and ADK23NS120038 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI COUGHLIN, DAVID G · 2021 to 2025
$828k
NIA NIH HHS P30 AG062429NINDS NIH HHS K08 NS090633NINDS NIH HHS K23 NS120038NINDS NIH HHS L30 NS123995
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Frontotemporal Lobar DegenerationMultiple System AtrophyParkinsonian DisordersSynucleinopathiesalpha-SynucleinHumansalpha-SynucleinGallyasmultiple system atrophyα-synuclein

Identifiers

PMID34847258
PMCPMC9097824
OpenAlexW3215085037

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.