Evidence map›Paper›PMID 34847201›Full record

Observational studyPloS one2021

Differences in the organisation of early pregnancy units and the effect of senior clinician presence, volume of patients and weekend opening on emergency hospital admissions: Findings from the VESPA Study.

Maria Memtsa, Venetia Goodhart, Gareth Ambler, Peter Brocklehurst, Edna Keeney, Sergio A Silverio, Zacharias Anastasiou, Jeff Round, Nazim Khan, Jennifer Hall and 4 more

Open access · goldAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. The paradox of early pregnancy care: Overtreatment amid systemic neglect.Acta obstetricia et gynecologica Scandinavica · 2025
    Article
  2. Article
  3. Ectopic pregnancy.Nature reviews. Disease primers · 2024
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 2 countries.

Maria MemtsaElizabeth Garrett Anderson Institute for Women's Health, University College London, London, United Kingdom.ORCID 0000-0002-5237-0914
Venetia GoodhartElizabeth Garrett Anderson Institute for Women's Health, University College London, London, United Kingdom.
Gareth AmblerDepartment of Statistical Science, University College London, London, United Kingdom.
Peter BrocklehurstBirmingham Clinical Trials Unit, Institute of Applied Health Research, University of Birmingham, Birmingham, United Kingdom.
Edna KeeneyPopulation Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom.
Sergio A SilverioElizabeth Garrett Anderson Institute for Women's Health, University College London, London, United Kingdom.
Zacharias AnastasiouDepartment of Statistical Science, University College London, London, United Kingdom.
Jeff RoundPopulation Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom.
Nazim KhanModelling and Analytical Systems Solutions (MASS) Ltd, Edinburgh, United Kingdom.
Jennifer HallElizabeth Garrett Anderson Institute for Women's Health, University College London, London, United Kingdom.
Geraldine BarrettElizabeth Garrett Anderson Institute for Women's Health, University College London, London, United Kingdom.
Ruth Bender-AtikThe Miscarriage Association, Wakefield, United Kingdom.
Judith StephensonElizabeth Garrett Anderson Institute for Women's Health, University College London, London, United Kingdom.
Davor JurkovicElizabeth Garrett Anderson Institute for Women's Health, University College London, London, United Kingdom.
University College Hospital · GBUniversity College London · GBUniversity of Bristol · GBMiscarriage Association · GBUniversity of Birmingham · GB

Funding

Department of Health 14/04/41
6 · The paper itself

Abstract

objectiveTo determine whether the participation of consultant gynaecologists in delivering early pregnancy care results in a lower rate of acute hospital admissions.

designProspective cohort study and emergency hospital care audit; data were collected as part of the national prospective mixed-methods VESPA study on the "Variations in the organization of EPAUs in the UK and their effects on clinical, Service and PAtient-centred outcomes".

setting44 Early Pregnancy Assessment Units (EPAUs) across the UK randomly selected in balanced numbers from eight pre-defined mutually exclusive strata.

participants6606 pregnant women (≥16 years old) with suspected first trimester pregnancy complications attending the participating EPAUs or Emergency Departments (ED) from December 2016 to July 2017. EXPOSURES: Planned and actual senior clinician presence, unit size, and weekend opening.

main outcome measuresUnplanned admissions to hospital following any visit for investigations or treatment for first trimester complications as a proportion of women attending EPAUs.

results205/6397 (3.2%; 95% CI 2.8-3.7) women were admitted following their EPAU attendance. The admission rate among 44 units ranged from 0% to 13.7% (median 2.8). Neither planned senior clinician presence (p = 0.874) nor unit volume (p = 0.247) were associated with lower admission rates from EPAU, whilst EPAU opening over the weekend resulted in lower admission rates (p = 0.027). 1445/5464 (26.4%; 95%CI 25.3 to 27.6) women were admitted from ED. There was little evidence of an association with planned senior clinician time (p = 0.280) or unit volume (p = 0.647). Keeping an EPAU open over the weekend for an additional hour was associated with 2.4% (95% CI 0.1% to 4.7%) lower odds of an emergency admission from ED.

conclusionsInvolvement of senior clinicians in delivering early pregnancy care has no significant impact on emergency hospital admissions for early pregnancy complications. Weekend opening, however, may be an effective way of reducing emergency admissions from ED.

Indexed as

Emergency Service, HospitalPatient AdmissionPhysiciansPregnancy Trimester, FirstPrenatal CareAdolescentAdultFemaleHumansPregnancyPregnancy ComplicationsProspective Studies

Identifiers

PMID34847201
PMCPMC8631630
OpenAlexW3211501702

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.