ReviewJMIR cancer2021
Chatbot for Health Care and Oncology Applications Using Artificial Intelligence and Machine Learning: Systematic Review.
Review in JMIR cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07410689 (SAFE.AI), which is not on this map. Cited by 184 papers, 9 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
SAFE.AI: Developing and Testing an AI-based Hybrid Chatbot for Financial Empowerment in Rural Cancer Care
Who cites it
184 citing papers in PubMed, 9 syntheses or guidelines pooled it.
- Use of AI to Predict and Support Medication Adherence in Patients With Breast Cancer: Systematic Review.JMIR cancer · 2026Pooled it
- Quality of Cancer-Related Information on New Media (2014-2023): Systematic Review and Meta-Analysis.Journal of medical Internet research · 2025Pooled it
- Impact of Online Interactive Decision Tools on Women's Decision-Making Regarding Breast Cancer Screening: Systematic Review and Meta-Analysis.Journal of medical Internet research · 2025Pooled it
- Comparative analysis of ChatGPT and Gemini (Bard) in medical inquiry: a scoping review.Frontiers in digital health · 2025Pooled it
- The multiple uses of artificial intelligence in exercise programs: a narrative review.Frontiers in public health · 2025Pooled it
- A systematic review of artificial intelligence-powered (AI-powered) chatbot intervention for managing chronic illness.Annals of medicine · 2024Pooled it
- Exploring the Role of Mobile Apps for Insomnia in Depression: Systematic Review.Journal of medical Internet research · 2024Pooled it
- Conversational AI and Vaccine Communication: Systematic Review of the Evidence.Journal of medical Internet research · 2023Pooled it
- Chatbot Artificial Intelligence for Genetic Cancer Risk Assessment and Counseling: A Systematic Review and Meta-Analysis.JCO clinical cancer informatics · 2023Pooled it
- The Impact of Chatbot Type and Normative Messaging on Chatbot Usage Intention Based on the Health Technology Acceptance Model: Randomized Controlled Trial.Journal of medical Internet research · 2026Trial
- Feasibility and Preliminary Effectiveness of the ChulaCancer Mobile Chatbot for Supportive Care of Patients With Breast or Colorectal Cancer Receiving Chemotherapy: Pilot Randomized Controlled Trial.JMIR formative research · 2026Trial
- A Telemedicine App for Nonrigid Facial Rehabilitation Training Enhanced by Efficient Fully Convolutional Neural Network With Residual Network (EffiFCNN-ResNet) to Improve Accessibility for Patients With Nasopharyngeal Carcinoma Cancer: Randomized Controlled Trial.JMIR mHealth and uHealth · 2026Trial
- Consistency and accuracy of different artificial intelligence models in evaluating longitudinal cracks and fractures of teeth.Odontology · 2026Article
- A Conversational Agent for Providing Personalized Preexposure Prophylaxis (PrEP) Support: Protocol for Chatbot Implementation and Evaluation.JMIR research protocols · 2026Article
- The Usability and Experience of Artificial Intelligence-Based Conversational Agents in Health Education for Cancer Patients: A Scoping Review.Journal of clinical nursing · 2026Article
- Conversational AI in Hereditary Cancer Care: Sociotechnical Study of Responsible Design Requirements.JMIR human factors · 2026Article
- Artificial intelligence for detection, grading, and prognostication in prostate cancer pathology: A scoping review.Histology and histopathology · 2026Article
- Neuropharmacology of Nicotine Addiction and Therapeutic Strategies for Smoking Cessation.Biology · 2026Review
- Finite State Machine-Guided Retrieval-Augmented Generation Improves Expert-Rated Acceptability of a Peripherally Inserted Central Catheter Self-Management Chatbot: Single-Center Content Validation Study.Journal of medical Internet research · 2026Article
- Introducing a Chatbot to Support Victim-Survivors of Domestic Abuse: Victim-Survivor Perspectives.Violence against women · 2026Article
124 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundChatbot is a timely topic applied in various fields, including medicine and health care, for human-like knowledge transfer and communication. Machine learning, a subset of artificial intelligence, has been proven particularly applicable in health care, with the ability for complex dialog management and conversational flexibility.
objectiveThis review article aims to report on the recent advances and current trends in chatbot technology in medicine. A brief historical overview, along with the developmental progress and design characteristics, is first introduced. The focus will be on cancer therapy, with in-depth discussions and examples of diagnosis, treatment, monitoring, patient support, workflow efficiency, and health promotion. In addition, this paper will explore the limitations and areas of concern, highlighting ethical, moral, security, technical, and regulatory standards and evaluation issues to explain the hesitancy in implementation.
methodsA search of the literature published in the past 20 years was conducted using the IEEE Xplore, PubMed, Web of Science, Scopus, and OVID databases. The screening of chatbots was guided by the open-access Botlist directory for health care components and further divided according to the following criteria: diagnosis, treatment, monitoring, support, workflow, and health promotion.
resultsEven after addressing these issues and establishing the safety or efficacy of chatbots, human elements in health care will not be replaceable. Therefore, chatbots have the potential to be integrated into clinical practice by working alongside health practitioners to reduce costs, refine workflow efficiencies, and improve patient outcomes. Other applications in pandemic support, global health, and education are yet to be fully explored.
conclusionsFurther research and interdisciplinary collaboration could advance this technology to dramatically improve the quality of care for patients, rebalance the workload for clinicians, and revolutionize the practice of medicine.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.