Evidence map›Paper›PMID 34846906›Full record

ArticleMolecular pharmaceutics2022

A Reactivity-Based

Filipa Mota, Victoria R Pell, Nisha Singh, Friedrich Baark, Edward Waters, Pragalath Sadasivam, Richard Southworth, Ran Yan

Open access · hybridAbstract read
In one paragraph

Article in Molecular pharmaceutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Filipa MotaSchool of Biomedical Engineering & Imaging Sciences, King's College London, King's Health Partners, St Thomas' Hospital, London SE1 7EH, United Kingdom.ORCID 0000-0002-2612-0778
Victoria R PellSchool of Biomedical Engineering & Imaging Sciences, King's College London, King's Health Partners, St Thomas' Hospital, London SE1 7EH, United Kingdom.
Nisha SinghSchool of Biomedical Engineering & Imaging Sciences, King's College London, King's Health Partners, St Thomas' Hospital, London SE1 7EH, United Kingdom.
Friedrich BaarkSchool of Biomedical Engineering & Imaging Sciences, King's College London, King's Health Partners, St Thomas' Hospital, London SE1 7EH, United Kingdom.
Edward WatersSchool of Biomedical Engineering & Imaging Sciences, King's College London, King's Health Partners, St Thomas' Hospital, London SE1 7EH, United Kingdom.
Pragalath SadasivamSchool of Biomedical Engineering & Imaging Sciences, King's College London, King's Health Partners, St Thomas' Hospital, London SE1 7EH, United Kingdom.
Richard SouthworthSchool of Biomedical Engineering & Imaging Sciences, King's College London, King's Health Partners, St Thomas' Hospital, London SE1 7EH, United Kingdom.
Ran YanSchool of Biomedical Engineering & Imaging Sciences, King's College London, King's Health Partners, St Thomas' Hospital, London SE1 7EH, United Kingdom.ORCID 0000-0002-0303-3196
St Thomas' Hospital · GB

Funding

British Heart Foundation PG/15/60/31629British Heart Foundation PG/16/43/32141Cancer Research UKDepartment of HealthMedical Research CouncilWellcome TrustWellcome Trust 212885/Z/18ZWellcome Trust WT 203148/Z/16/Z
6 · The paper itself

Abstract

Oxidative stress underlies the pathology of many human diseases, including the doxorubicin-induced off-target cardiotoxicity in cancer chemotherapies. Since current diagnostic procedures are only capable of monitoring cardiac function, a noninvasive means of detecting biochemical changes in redox status prior to irreversible functional changes is highly desirable for both early diagnosis and prognosis. We designed a novel

Indexed as

AnimalsCardiotoxicityDisease Models, AnimalDoxorubicinEchocardiographyFluorine RadioisotopesMaleMiceMice, Inbred C57BLOxidative StressPositron-Emission TomographyRatsRats, WistarDoxorubicinFluorine Radioisotopescardiotoxicityfluorine-18oxidative stressPET imagingreactive oxygen species

Identifiers

PMID34846906
PMCPMC8728736
OpenAlexW3215153289

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.