Evidence map›Paper›PMID 34846863›Full record

ArticleBiomacromolecules2021

Polymer-Mediated Cryopreservation of Bacteriophages.

Huba L Marton, Kathryn M Styles, Peter Kilbride, Antonia P Sagona, Matthew I Gibson

Open access · hybridAbstract read
In one paragraph

Article in Biomacromolecules, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Huba L MartonDepartment of Chemistry, University of Warwick, Coventry CV4 7AL, U.K.ORCID 0000-0001-7547-6001
Kathryn M StylesSchool of Life Sciences, University of Warwick, Coventry CV4 7AL, U.K.
Peter KilbrideAsymptote, Cytiva, Chivers Way, Cambridge CB24 9BZ, U.K.
Antonia P SagonaSchool of Life Sciences, University of Warwick, Coventry CV4 7AL, U.K.
Matthew I GibsonDepartment of Chemistry, University of Warwick, Coventry CV4 7AL, U.K.ORCID 0000-0002-8297-1278
University of Warwick · GBAsymptote (United Kingdom) · GB

Funding

Biotechnology and Biological Sciences Research Council BB/M01116X/1European Research Council 866056
6 · The paper itself

Abstract

Bacteriophages (phages, bacteria-specific viruses) have biotechnological and therapeutic potential. To apply phages as pure or heterogeneous mixtures, it is essential to have a robust mechanism for transport and storage, with different phages having very different stability profiles across storage conditions. For many biologics, cryopreservation is employed for long-term storage and cryoprotectants are essential to mitigate cold-induced damage. Here, we report that poly(ethylene glycol) can be used to protect phages from cold damage, functioning at just 10 mg·mL

Indexed as

BacteriophagesCryopreservationCryoprotective AgentsFreezingHumansPolymersCryoprotective AgentsPolymers

Identifiers

PMID34846863
PMCPMC8672357
OpenAlexW3216569806

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.