Evidence map›Paper›PMID 34846602›Full record

ArticleEuropean journal of nutrition2022

A healthy dietary pattern with a low inflammatory potential reduces the risk of gestational diabetes mellitus.

Lotta Pajunen, Liisa Korkalo, Ella Koivuniemi, Noora Houttu, Outi Pellonperä, Kati Mokkala, Nitin Shivappa, James R Hébert, Tero Vahlberg, Kristiina Tertti and 1 more

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in European journal of nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01922791 (Placebo-controlled Intervention Study for Maternal and Child Health), which is not on this map. Cited by 17 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 4 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01922791 nacompletednot on this map

Placebo-controlled Intervention Study for Maternal and Child Health

TypeinterventionalSponsorTurku University HospitalRan2013 to 2023Enrolled439ConditionsPregnancy, Obesity, Gestational Diabetes Mellitus, AdiposityArmsComparison of probiotics, fish oil and their combination to placebo
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 4 syntheses or guidelines pooled it, 34 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Lotta PajunenInstitute of Biomedicine, Research Centre for Integrative Physiology and Pharmacology, University of Turku, 20520, Turku, Finland. loevpa@utu.fi.ORCID http://orcid.org/0000-0001-5090-0662
Liisa KorkaloDepartment of Food and Nutrition, University of Helsinki, 00014, Helsinki, Finland.ORCID http://orcid.org/0000-0002-0525-9877
Ella KoivuniemiInstitute of Biomedicine, Research Centre for Integrative Physiology and Pharmacology, University of Turku, 20520, Turku, Finland.ORCID http://orcid.org/0000-0002-5751-3064
Noora HouttuInstitute of Biomedicine, Research Centre for Integrative Physiology and Pharmacology, University of Turku, 20520, Turku, Finland.ORCID http://orcid.org/0000-0002-1350-2187
Outi PellonperäDepartment of Obstetrics and Gynecology, University of Turku and Turku University Hospital, 20520, Turku, Finland.ORCID http://orcid.org/0000-0001-9272-2278
Kati MokkalaInstitute of Biomedicine, Research Centre for Integrative Physiology and Pharmacology, University of Turku, 20520, Turku, Finland.ORCID http://orcid.org/0000-0002-0354-5546
Nitin ShivappaCancer Prevention and Control Program and Department of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, SC, 29208, USA.ORCID http://orcid.org/0000-0003-0441-8896
James R HébertCancer Prevention and Control Program and Department of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, SC, 29208, USA.ORCID http://orcid.org/0000-0002-0677-2672
Tero VahlbergInstitute of Clinical Medicine, Biostatistics, University of Turku, 20014, Turku, Finland.ORCID http://orcid.org/0000-0002-4935-3056
Kristiina TerttiDepartment of Obstetrics and Gynecology, University of Turku and Turku University Hospital, 20520, Turku, Finland.ORCID http://orcid.org/0000-0001-8950-3103
Kirsi LaitinenInstitute of Biomedicine, Research Centre for Integrative Physiology and Pharmacology, University of Turku, 20520, Turku, Finland.ORCID http://orcid.org/0000-0001-5245-8118
University of Turku · FIUniversity of South Carolina · USUniversity of Helsinki · FI

Funding

Academy of Finland 258606
6 · The paper itself

Abstract

purposeAn optimal diet for lowering the risk of gestational diabetes mellitus (GDM) is still to be defined, but may comprise of nutrient intakes, dietary patterns, diet quality, and eating frequency. This study was designed to investigate the contribution of diet in developing GDM in a comprehensive way.

methodsThe dietary intake of overweight or obese women, a risk group for GDM (n = 351), was assessed using 3-day food diaries and diet quality questionnaires in early pregnancy. Eating frequency and nutrient intakes were calculated, and dietary patterns identified using principal component analysis. The inflammatory potential of the diet was determined by calculating the dietary inflammatory index (DII

resultsHigher adherence to 'healthier dietary pattern' characterized by consumptions of vegetables and rye bread associated with a reduced risk of GDM (adjusted OR 0.27, 95% CI 0.11-0.70). Higher E-DII score, indicating pro-inflammatory diet, was associated with a 27% higher risk of GDM (adjusted OR 1.27; 95% CI 1.08-1.49) for each E-DII point. In the evaluation of nutrient intakes, total fat, saturated fatty acids (SFAs), and trans fatty acids were higher and fiber lower in women developing GDM compared to women not developing GDM (all p < 0.05). Intakes of total fat, SFAs, and trans fatty acids were also significant predictors for GDM (all p < 0.05).

conclusionsThe results emphasize the importance of an overall healthy diet and limitation of foods with SFAs, and other nutrients with a high inflammatory potential in reducing the risk of GDM.

trial registrationClinicalTrials.gov Identifier: NCT01922791, August 14, 2013.

Indexed as

Diabetes, GestationalDietDietary FiberDiet RecordsFemaleGlucose Tolerance TestHumansPregnancyDietary FiberDietary inflammatory indexDietary patternGestational diabetes mellitusSaturated fatty acid

Identifiers

PMID34846602
PMCPMC8921111
OpenAlexW3217779593

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.