Evidence map›Paper›PMID 34846389›Full record

ArticleChemical communications (Cambridge, England)2021

Supramolecular capture of highly polar amidosquaraine dye in water with nanomolar affinity and large turn-on fluorescence.

Madushani Dharmarwardana, Janel M Dempsey, Sasha Padilla-Coley, Tia S Jarvis, Kejia Shi, Kirk M Atkinson, Bradley D Smith

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemical communications (Cambridge, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Madushani DharmarwardanaDepartment of Chemistry and Biochemistry, 251 Nieuwland Science Hall, University of Notre Dame, Notre Dame, IN 46556, USA. smith.115@nd.edu.ORCID http://orcid.org/0000-0002-3086-047X
Janel M DempseyDepartment of Chemistry and Biochemistry, 251 Nieuwland Science Hall, University of Notre Dame, Notre Dame, IN 46556, USA. smith.115@nd.edu.ORCID http://orcid.org/0000-0001-8850-7292
Sasha Padilla-ColeyDepartment of Chemistry and Biochemistry, 251 Nieuwland Science Hall, University of Notre Dame, Notre Dame, IN 46556, USA. smith.115@nd.edu.ORCID http://orcid.org/0000-0002-5146-170X
Tia S JarvisDepartment of Chemistry and Biochemistry, 251 Nieuwland Science Hall, University of Notre Dame, Notre Dame, IN 46556, USA. smith.115@nd.edu.ORCID http://orcid.org/0000-0002-0260-2123
Kejia ShiDepartment of Chemistry and Biochemistry, 251 Nieuwland Science Hall, University of Notre Dame, Notre Dame, IN 46556, USA. smith.115@nd.edu.ORCID http://orcid.org/0000-0001-7313-2205
Kirk M AtkinsonDepartment of Chemistry and Biochemistry, 251 Nieuwland Science Hall, University of Notre Dame, Notre Dame, IN 46556, USA. smith.115@nd.edu.ORCID http://orcid.org/0000-0001-9827-1949
Bradley D SmithDepartment of Chemistry and Biochemistry, 251 Nieuwland Science Hall, University of Notre Dame, Notre Dame, IN 46556, USA. smith.115@nd.edu.ORCID http://orcid.org/0000-0003-4120-3210
University of Notre Dame · US

Funding

Molecular Probes for Biomembrane RecognitionR35GM136212 · NIGMS · UNIVERSITY OF NOTRE DAME · PI Bradley D Smith · 2020 to 2026
$2.5M
NIGMS NIH HHS R35 GM136212
6 · The paper itself

Abstract

A supramolecular dye-capture system comprising anionic amidosquaraine guest and macrocyclic tetralactam host exhibits nanomolar affinity and "turn on" visible fluorescence. Utility is demonstrated with a new fluorescent assay for liposome leakage induced by the biomedically important enzyme phospholipase A

Identifiers

PMID34846389
PMCPMC8689413
OpenAlexW3217295540

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.