Observational studyClinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
Utility of Blood Cellular Indices in the Risk Stratification of Patients Presenting with Acute Pulmonary Embolism.
Observational study in Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 18 citations in OpenAlex.
- The Clinical and Hematological Markers of Pulmonary Embolism: Multicenter Retrospective Study in Mongolia.Hematology reports · 2026Article
- Prognostic Value of Initial Inflammatory Biomarkers, ECG Findings, and Computed Tomography in the Assessment of Acute Pulmonary Embolism Severity.Medicina (Kaunas, Lithuania) · 2025Observational
- The Prognostic Role of Hematological Markers in Acute Pulmonary Embolism: Enhancing Risk Stratification.Medicina (Kaunas, Lithuania) · 2025Article
- The Prognostic Value of Inflammatory Indices in Acute Pulmonary Embolism.Diagnostics (Basel, Switzerland) · 2025Article
- Development and Evaluation of an Innovative Inflammatory Prognostic Score for Predicting Long-Term Mortality in Patients With Pulmonary Embolism.Mediators of inflammation · 2025Article
- Development and validation of a novel screening tool for deep vein thrombosis in patients with spinal cord injury: A five-year cross-sectional study.Spinal cord · 2024Article
- Neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio as predictors of mortality in acute pulmonary embolism: A systematic review and meta-analysis.Pakistan journal of medical sciences · 2024Review
- Associations of RBC counts and incidence of DVT in patients with spinal cord injury: a five year observational retrospective study.Journal of orthopaedic surgery and research · 2024Observational
- Causal association between circulating blood cell traits and pulmonary embolism: a mendelian randomization study.Thrombosis journal · 2024Article
- Role of serum biomarkers in predicting management strategies for acute pulmonary embolism.Heliyon · 2023Article
- Association of Blood Leukocytes and Hemoglobin with Hospital Mortality in Acute Pulmonary Embolism.Journal of clinical medicine · 2023Article
- The Association Between Mean Corpuscular Hemoglobin Concentration and Prognosis in Patients with Acute Pulmonary Embolism: A Retrospective Cohort Study.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/HemostasisArticle
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
Pulmonary embolism (PE) clinical manifestations vary widely, and that scope is not fully captured by current all-cause mortality risk models. PE is associated with inflammatory, coagulation, and hemostatic imbalances so blood cellular indices may be prognostically useful. Complete blood count (CBC) data may improve current risk models like the simplified pulmonary embolism severity index (sPESI) for all-cause mortality, offering greater accuracy and analytic ability. Acute PE patients (n = 228) with confirmatory diagnostic imaging were followed for all-cause mortality. Blood cellular indices were assessed for association to all-cause mortality and were supplemented into sPESI using multivariate logistic regression. Multiple blood cellular indices were found to be significantly associated with all-cause mortality in acute PE. sPESI including red cell distribution width, hematocrit and neutrophil-lymphocyte ratio had better predictive ability as compared to sPESI alone (AUC: 0.852 vs 0.754). Blood cellular indices contribute an inflammatory and hemodynamic perspective not currently included in sPESI. CBC with differential is a widely used, low-cost test that can augment current risk stratification tools for all-cause mortality in acute PE patients.
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