Evidence map›Paper›PMID 34846128›Full record

ArticleBiochemistry2021

Insight into the Phospholipid-Binding Preferences of Kir3.4.

Pei Qiao, Samantha Schrecke, Jixing Lyu, Yun Zhu, Tianqi Zhang, Amanda Benavides, Arthur Laganowsky

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biochemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Pei QiaoDepartment of Biochemistry and Biophysics, Texas A&M University, College Station, Texas 77843, United States.
Samantha SchreckeDepartment of Chemistry, Texas A&M University, College Station, Texas 77843, United States.
Jixing LyuDepartment of Chemistry, Texas A&M University, College Station, Texas 77843, United States.
Yun ZhuDepartment of Chemistry, Texas A&M University, College Station, Texas 77843, United States.
Tianqi ZhangDepartment of Chemistry, Texas A&M University, College Station, Texas 77843, United States.
Amanda BenavidesDepartment of Chemistry, Texas A&M University, College Station, Texas 77843, United States.
Arthur LaganowskyDepartment of Chemistry, Texas A&M University, College Station, Texas 77843, United States.ORCID 0000-0001-5012-5547
Texas A&M University · US

Funding

Waters Select Series Cyclic IMS for P41 Native MS Resource Application to Alzheimer's DiseaseP41GM128577 · NIGMS · OHIO STATE UNIVERSITY · PI WYSOCKI, VICKI H. · 2018 to 2022
$7.6M
Native ion mobility mass spectrometry studies of potassium inward rectifier channels: insight into gating and lipid bindingDP2GM123486 · NIGMS · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI LAGANOWSKY, ARTHUR D · 2016 to 2016
$2.2M
Development of high resolution mobility measurements for structural biologyR01GM121751 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI CLEMMER, DAVID E., LAGANOWSKY, ARTHUR D · 2017 to 2020
$1.7M
Innovative Native Ion Mobility Approaches for Transformational Measurements in Structural BiologyR01GM138863 · NIGMS · TEXAS A&M UNIVERSITY · PI CLOWERS, BRIAN, LAGANOWSKY, ARTHUR D · 2020 to 2023
$1.2M
NIGMS NIH HHS DP2 GM123486NIGMS NIH HHS P41 GM128577NIGMS NIH HHS R01 GM121751NIGMS NIH HHS R01 GM138863
6 · The paper itself

Abstract

The G-protein-gated inwardly rectifying potassium channel 4 (Kir3.4) subunit forms functional tetramers. Previous studies have established that phosphatidylinositol 4,5-bisphosphate (PI(4,5)P

Indexed as

Amino Acid SubstitutionBinding, CompetitiveBinding SitesBoron CompoundsFluorescent DyesG Protein-Coupled Inwardly-Rectifying Potassium ChannelsHumansModels, MolecularPhosphatidylinositolsPhospholipidsPoint MutationProtein BindingProtein Structure, QuaternaryRecombinant ProteinsSpectrometry, Mass, Electrospray Ionization4,4-difluoro-4-bora-3a,4a-diaza-s-indaceneBoron CompoundsFluorescent DyesG Protein-Coupled Inwardly-Rectifying Potassium ChannelsKCNJ5 protein, humanKCNJ6 protein, humanPhosphatidylinositolsPhospholipidsRecombinant Proteins

Identifiers

PMID34846128
PMCPMC9569133
OpenAlexW3216767231

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.