Evidence map›Paper›PMID 34845984›Full record

ArticleeLife2021

Daily electrical activity in the master circadian clock of a diurnal mammal.

Beatriz Bano-Otalora, Matthew J Moye, Timothy Brown, Robert J Lucas, Casey O Diekman, Mino Dc Belle

Open access · goldAbstract read
In one paragraph

Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
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  4. Review
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  8. A Subcircuit in the Suprachiasmatic Nucleus Generates Wakefulness.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  9. Article
  10. Article
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  12. Review
  13. Diurnal Variation of Brain Activity in the Human Suprachiasmatic Nucleus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  14. Article
  15. Review
  16. Article
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  19. Inhibitory responses to retinohypothalamic tract stimulation in the circadian clock of the diurnal rodent Rhabdomys pumilio.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2022
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Beatriz Bano-Otalora *Centre for Biological Timing, Faculty of Biology Medicine and Health, University of Manchester, Manchester, United Kingdom.ORCID 0000-0003-4694-9943
Matthew J Moye *Department of Mathematical Sciences, New Jersey Institute of Technology, Newark, United States.
Timothy BrownCentre for Biological Timing, Faculty of Biology Medicine and Health, University of Manchester, Manchester, United Kingdom.
Robert J LucasCentre for Biological Timing, Faculty of Biology Medicine and Health, University of Manchester, Manchester, United Kingdom.ORCID 0000-0002-1088-8029
Casey O DiekmanDepartment of Mathematical Sciences, New Jersey Institute of Technology, Newark, United States.ORCID 0000-0002-4711-1395
Mino Dc BelleInstitute of Biomedical and Clinical Sciences, University of Exeter Medical School, University of Exeter, Exeter, United Kingdom.ORCID 0000-0002-4917-957X
University of Manchester · GBNew Jersey Institute of Technology · USUniversity of Exeter · GB

Funding

Biotechnology and Biological Sciences Research Council BB/N014901/1Biotechnology and Biological Sciences Research Council BB/P009182/1Biotechnology and Biological Sciences Research Council BB/S01764X/1Wellcome Trust 210684/Z/18/Z
6 · The paper itself

Abstract

Circadian rhythms in mammals are orchestrated by a central clock within the suprachiasmatic nuclei (SCN). Our understanding of the electrophysiological basis of SCN activity comes overwhelmingly from a small number of nocturnal rodent species, and the extent to which these are retained in day-active animals remains unclear. Here, we recorded the spontaneous and evoked electrical activity of single SCN neurons in the diurnal rodent

Indexed as

AnimalsCircadian ClocksMuridaeNeuronsSuprachiasmatic Nucleuscircadian rhythmscomputational biologydiurnalityelectrical activitymathematical modellingneurosciencesuprachiasmatic nucleussystems biology

Identifiers

PMID34845984
PMCPMC8631794
OpenAlexW3208627804

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.