Evidence map›Paper›PMID 34845981›Full record

ArticleThe Journal of general virology2021

Revisiting dengue virus-mosquito interactions: molecular insights into viral fitness.

Tanamas Siriphanitchakorn, R Manjunatha Kini, Eng Eong Ooi, Milly M Choy

Open access · hybridAbstract read
In one paragraph

Article in The Journal of general virology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Horizons of the Future: Preparedness and Response.Current topics in microbiology and immunology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Tanamas SiriphanitchakornProgramme in Emerging Infectious Diseases, Duke-NUS Medical School, 169857 Singapore, Singapore.
R Manjunatha KiniDepartment of Biological Sciences, Faculty of Science, National University of Singapore, 117558 Singapore, Singapore.
Eng Eong OoiProgramme in Emerging Infectious Diseases, Duke-NUS Medical School, 169857 Singapore, Singapore.
Milly M ChoyProgramme in Emerging Infectious Diseases, Duke-NUS Medical School, 169857 Singapore, Singapore.
National University of Singapore · SGDuke-NUS Medical School · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dengue virus (DENV), like other viruses, closely interacts with the host cell machinery to complete its life cycle. Over the course of infection, DENV interacts with several host factors with pro-viral activities to support its infection. Meanwhile, it has to evade or counteract host factors with anti-viral activities which inhibit its infection. These molecular virus-host interactions play a crucial role in determining the success of DENV infection. Deciphering such interactions is thus paramount to understanding viral fitness in its natural hosts. While DENV-mammalian host interactions have been extensively studied, not much has been done to characterize DENV-mosquito host interactions despite its importance in controlling DENV transmission. Here, to provide a snapshot of our current understanding of DENV-mosquito interactions, we review the literature that identified host factors and cellular processes related to DENV infection in its mosquito vectors,

Indexed as

AedesAnimalsCell LineDengueDengue VirusHost Microbial InteractionsHumansLife Cycle StagesMosquito VectorsTranscriptomeVirus Replicationdengue virusmosquitoesviral fitnessvirus-host interactions

Identifiers

PMID34845981
PMCPMC8742994
OpenAlexW3215697476

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.