Evidence map›Paper›PMID 34845874›Full record

ArticleJournal of Korean medical science2021

Clinical Characteristics and Treatment Outcomes of Patients with Hepatitis C Virus and Human Immunodeficiency Virus Coinfection: Experience at a Single Center in Korea.

Dae Hyun Lim, Jae Yoon Jeong, Seongwoo Nam, Jongkyoung Choi, Hyeok Choon Kwon, Yong Bum Yoon, Yeonjae Kim, BumSik Chin

Open access · goldAbstract read
In one paragraph

Article in Journal of Korean medical science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Dae Hyun LimDivision of Gastroenterology and Hepatology, Department of Internal Medicine, National Medical Center, Seoul, Korea.ORCID https://orcid.org/0000-0001-7684-1816
Jae Yoon JeongDivision of Gastroenterology and Hepatology, Department of Internal Medicine, National Medical Center, Seoul, Korea. jyjeong@nmc.or.kr.ORCID https://orcid.org/0000-0002-3624-3261
Seongwoo NamDivision of Gastroenterology and Hepatology, Department of Internal Medicine, National Medical Center, Seoul, Korea. seongwoo.nam@nmc.or.kr.ORCID https://orcid.org/0000-0003-1586-0380
Jongkyoung ChoiDivision of Gastroenterology and Hepatology, Department of Internal Medicine, National Medical Center, Seoul, Korea.ORCID https://orcid.org/0000-0003-1514-7008
Hyeok Choon KwonDivision of Gastroenterology and Hepatology, Department of Internal Medicine, National Medical Center, Seoul, Korea.ORCID https://orcid.org/0000-0003-3740-3033
Yong Bum YoonDivision of Gastroenterology and Hepatology, Department of Internal Medicine, National Medical Center, Seoul, Korea.ORCID https://orcid.org/0000-0002-4217-7619
Yeonjae KimDivision of Infectious Diseases, Department of Internal Medicine, National Medical Center, Seoul, Korea.ORCID https://orcid.org/0000-0003-4144-9077
BumSik ChinDivision of Infectious Diseases, Department of Internal Medicine, National Medical Center, Seoul, Korea.ORCID https://orcid.org/0000-0003-3021-1434
National Medical Center · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBecause of the very low incidence of human immunodeficiency virus (HIV) coinfection in Korea, data on hepatitis C virus (HCV)/HIV coinfection are limited. This study aimed to investigate the clinical characteristics and treatment outcomes of patients with HCV/HIV coinfection in Korea.

methodsWe performed a retrospective cohort study of all HCV-monoinfected and HCV/HIV-coinfected patients treated with antivirals at National Medical Center in Seoul, Korea, between January 2009 and March 2020.

resultsWe enrolled 220 HCV-monoinfected and 23 HCV/HIV-coinfected patients treated with antivirals. The HCV/HIV-coinfected patients were younger (HCV vs. HCV/HIV: 57.3 ± 11.3 vs. 40.7 ± 10.1 years,

conclusionIn Korea, the HCV/HIV-coinfected patients who received antiviral treatment were younger, had higher proportion of men and incidence of genotype 1a, and had less advanced fibrosis than the HCV-monoinfected patients. In actual clinical settings, HCV/HIV-coinfected patients show excellent SVR to DAA treatment, similar to HCV-monoinfected patients.

Indexed as

AdultAntiviral AgentsDrug Therapy, CombinationFemaleGenotypeHepacivirusHepatitis CHIV InfectionsHumansLiver CirrhosisMaleMiddle AgedRetrospective StudiesRNA, ViralSustained Virologic ResponseTreatment OutcomeAntiviral AgentsRNA, ViralDirect-Acting AntiviralsHepatitis C VirusHuman Immunodeficiency Virus

Identifiers

PMID34845874
PMCPMC8629715
OpenAlexW3212775918

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.