Evidence map›Paper›PMID 34845864›Full record

SynthesisClinical and experimental dental research2022

Stability of biomaterials used in adjunct to coronally advanced flap: A systematic review and network meta-analysis.

Sourav Panda, Shahnawaz Khijmatgar, Heber Arbildo-Vega, Abhaya Chandra Das, Manoj Kumar, Mohit Das, Leonardo Mancini, Massimo Del Fabbro

Abstract readSystematic ReviewNetwork Meta-Analysis
In one paragraph

Synthesis in Clinical and experimental dental research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
  6. A New Matrix for Soft Tissue Management.Journal of clinical medicine · 2022
    Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sourav PandaDepartment of Periodontics and Oral Implantology, Institute of Dental Sciences, Siksha O Anusandhan (Deemed to be) University, Bhubaneswar, Odisha, India.ORCID 0000-0002-0198-748X
Shahnawaz KhijmatgarDepartment of Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Italy.ORCID 0000-0002-9177-3505
Heber Arbildo-VegaDepartment of General Dentistry, Dentistry School, Universidad San Martín de Porres, Chiclayo, Peru.ORCID 0000-0003-3689-7502
Abhaya Chandra DasDepartment of Periodontics and Oral Implantology, Institute of Dental Sciences, Siksha O Anusandhan (Deemed to be) University, Bhubaneswar, Odisha, India.ORCID 0000-0001-7832-3406
Manoj KumarDepartment of Periodontics and Oral Implantology, Institute of Dental Sciences, Siksha O Anusandhan (Deemed to be) University, Bhubaneswar, Odisha, India.ORCID 0000-0002-8775-0589
Mohit DasDepartment of Periodontics and Oral Implantology, Institute of Dental Sciences, Siksha O Anusandhan (Deemed to be) University, Bhubaneswar, Odisha, India.ORCID 0000-0001-8224-5500
Leonardo ManciniDepartment of life health and environmental sciences, University of L'Aquila, Italy.ORCID 0000-0002-7030-155X
Massimo Del FabbroDepartment of Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Italy.ORCID 0000-0001-7144-0984

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThe objective of this network meta-analysis was to rank different biomaterials used in adjunct to coronally advanced flap (CAF), based on their performance in root-coverage for Miller's Class I and II gingival recessions. MATERIALS AND

methodsAn electronic database search was carried out in PUBMED, CENTRAL, SCOPUS, and EMBASE to identify the eligible articles and compiled into the citation manager to remove the duplicates. The primary outcome was keratinized gingival tissue width (KGW) and percentage of root coverage (%RC). The treatment effect of different biomaterials was estimated using predictive interval plots and ranked based on biomaterials performance, using multidimensional scale ranking.

resultsCAF + connective tissue graft (CTG), CAF + platelet concentrate matrix (PCM) and acellular dermal matrix (ADM) ranked at the top positions in performance in improving KGW. The highest ranked materials in improving percentage of root coverage in gingival recession were CAF + collagen matrix (CM) + gingival fibroblasts (GF), CAF + ADM + platelet rich plasma (PRP) and CAF + ADM, as compared to CAF alone.

conclusionCTG, ADM, platelet concentrates, and CM + GFs, when used in adjunct to CAF, showed improved stability over ≥12 months of follow-up, better percentage of root coverage, and improved keratinized gingival width.

Indexed as

Biocompatible MaterialsGingival RecessionCollagenHumansTooth RootTreatment OutcomeBiocompatible MaterialsCollagenCAFclinical attachment levelkeratinised tissue widthnetwork meta-analysisoralrecession heightrecession widthregenerationroot coveragesoft tissuesystematic review

Identifiers

PMID34845864
PMCPMC8874057

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.