SynthesisUnited European gastroenterology journal2021
Diversion proctocolitis and the problem of the forgotten rectum in inflammatory bowel diseases: A systematic review.
Synthesis in United European gastroenterology journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
What it found
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- Diversion proctocolitis and the problem of the forgotten rectum in inflammatory bowel diseases: A systematic review.United European gastroenterology journal · 2021Pooled it
- Diversion proctitis during staged restorative proctocolectomy with ileal pouch anal anastomosis is not associated with subsequent cuffitis.International journal of colorectal disease · 2026Article
- Benign functional anorectal conditions: a multi-centre analysis of rectal stump symptomatology in patients undergoing stoma formation.Techniques in coloproctology · 2026Article
- The Rectal Stump During and After Subtotal Colectomy for Ulcerative Colitis: A Narrative Review of Surgical Strategies, Medical Management Options, and Cancer Surveillance Recommendations.Journal of clinical medicine · 2026Review
- Ileostoma as a promising tool in pathophysiological study and clinical intervention: a review from bench to beside.Frontiers in immunology · 2026Review
- Endoscopic Evaluation and Management of Diversion Pouchitis and Strictures: In Comparison With Strictures in Nondiverted Pouches.Gastro hep advances · 2026Article
- Changes in Gut Microbiome According to Probiotic Intake in Rectal Cancer Patients Undergoing Diverting Stoma Repair: Study Protocol.Journal of clinical medicine · 2025Article
- Colorectal cancer at the anastomotic site following childhood surgery for hirschsprung disease: a rare case report.World journal of surgical oncology · 2025Article
- Routine Endoscopy Prior to Surgical Ostomy Closure: An Obsolete Concept.Digestive diseases and sciences · 2023Article
- Dysbiosis of gut microbiota during fecal stream diversion in patients with colorectal cancer.Gut pathogens · 2023Article
- Interaction between the intestinal flora and the severity of diversion colitis after low anterior resection of rectal cancer.Frontiers in oncology · 2023Article
- Young GI angle: Challenges and opportunities as a trainee editor: The United European Gastroenterology journal experience.United European gastroenterology journal · 2022Article
- Guidelines, top-notch science & social media-Jump on the bandwagon.United European gastroenterology journal · 2022Article
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimsDiversion proctocolitis (DP) is a non-specific mucosal inflammation arising in the defunctionalized colon and/or rectum following faecal diversion (colostomy, ileostomy). Differential diagnosis of DP from the underlying disease in patients with inflammatory bowel diseases (IBD) is often unclear. As a result, it might be difficult to undertake any specific treatment. We aimed to systematically review the literature evidence on DP in IBD patients.
methodsFor this qualitative systematic review, we searched PubMed, EMBASE and Scopus to identify all studies published until July 2021 including IBD patients affected by DP.
resultsOverall, 37 papers published between 1982 and 2021 were included. A total of 1.211 IBD patients were included: 613 UC (50.6%), 524 CD (43.3%), 66 IBD-unclassified (IBD-U) (5.4%), 8 unspecified patients (0.7%). Most patients with DP are asymptomatic, although inflammation is detectable in almost all patients with a rectal stump. Reduced short-chain fatty acids and an altered microbiome, may trigger mucosal inflammation and have been proposed as causing factors. An increased risk of developing cancer on DP has been reported in patients with a history of previous dysplasia/cancer.
conclusionsThe etiopathogenesis of DP is still unknown. The efficacy of mesalamine, corticosteroids or short-chain fatty acids has not been proven by randomized trials yet. Since the incidence of cancer of the rectal stump can reach 4.5 per 1.000 diverted patients-year, IBD patients undergoing subtotal colectomy with end-ileostomy should undergo close endoscopic surveillance, being eventually counseled for surgery with or without the restoration of the intestinal continuity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.