Evidence map›Paper›PMID 34845599›Full record

ArticleInternational ophthalmology2022

Systemic diseases and their association with open-angle glaucoma in the population of Stockholm.

Per Wändell, Axel C Carlsson, Gunnar Ljunggren

Open access · hybridAbstract read
In one paragraph

Article in International ophthalmology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Per WändellDepartment of Neurobiology, Care Sciences and Society, Division of Family Medicine and Primary Care, Karolinska Institutet, Alfred Nobels Allé 23, 141 83, Huddinge, Sweden. per.wandell@ki.se.ORCID http://orcid.org/0000-0001-5169-2965
Axel C CarlssonDepartment of Neurobiology, Care Sciences and Society, Division of Family Medicine and Primary Care, Karolinska Institutet, Alfred Nobels Allé 23, 141 83, Huddinge, Sweden.
Gunnar LjunggrenDepartment of Neurobiology, Care Sciences and Society, Division of Family Medicine and Primary Care, Karolinska Institutet, Alfred Nobels Allé 23, 141 83, Huddinge, Sweden.
Karolinska Institutet · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWe aimed to study open-angle glaucoma in association with somatic comorbidities in the total population of adults in Region Stockholm.

methodsThe study population included all living persons aged 19 years and above who resided in Stockholm County, Sweden, on 1 January 2017 (N = 1 703 675). Subjects with specified diseases were identified with data from all registered consultations and hospital stays during 2008-2019. As outcome, the risk of being associated with a diagnosis of open-angle glaucoma was identified during 2012-2018. Analyses were performed by gender, controlling for age and socio-economic status. Age-adjusted odds ratios (ORs) with 95% confidence intervals (95% CI) for women and men with open-angle glaucoma, using individuals without this as referents, were calculated. Socio-economic status was assessed based on the neighbourhood the subjects lived in.

resultsIn total, 16,299 cases of open-angle glaucoma were identified during 2012-2018, 9204 women and 7095 men. Higher fully adjusted OR (95% CI) for risk of being associated with open-angle glaucoma was for women and men with diabetes 1.138 (1.074-1.207) and 1.216 (1.148-1.289), cancer 1.175 (1.120-1.233) and 1.106 (1.048-1.166), hypertension 1.372 (1.306-1.440) and 1.243 (1.179-1.311); and for women with thyroid diseases 1.086 (1.030-1.146), chronic lung diseases 1.153 (1.093-1.216), and inflammatory arthropathies 1.132 (1.006-1.275). Higher glaucoma incidence was observed in individuals residing in high socio-economic status neighbourhoods.

conclusionThe risk of glaucoma is increased in some somatic diseases, especially in individuals with diabetes, hypertension and cancer; and in higher socio-economic neighbourhoods as compared to lower socio-economic neighbourhoods.

Indexed as

Diabetes MellitusGlaucoma, Open-AngleHypertensionNeoplasmsAdultComorbidityFemaleHumansMaleRisk FactorsAdministrative databasesAge differencesEpidemiologyOpen-angle glaucomaSex differencesSocio-economic areas

Identifiers

PMID34845599
PMCPMC9122867
OpenAlexW3215219768

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.